Congenital rubella syndrome: a case report

Authors

  • Mahmoud M. Osman Department of Pediatrics, Neonatal Intensive Care Unit, Alyamamah Hospital, Riyadh, KSA
  • Meryat T. Zakaria Department of Pediatrics, Faculty of Medicine, Cairo University, Egypt
  • Mutassem F. Alnofal Department of Pediatrics, Neonatal Intensive Care Unit, Alyamamah Hospital, Riyadh, KSA
  • Sulafa A. Hamdoun Department of Pediatrics, Neonatal Intensive Care Unit, Alyamamah Hospital, Riyadh, KSA
  • Mohammed S. Alissa Department of Pediatrics, Neonatal Intensive Care Unit, Alyamamah Hospital, Riyadh, KSA

DOI:

https://doi.org/10.18203/2349-3291.ijcp20204052

Keywords:

Cataract, Congenital infection, Congenital heart disease, Congenital rubella, Sensorineural hearing loss

Abstract

Currently, rubella virus infections are very rare in many countries, and may not be recognized promptly.  However, congenital rubella syndrome still appears, often in infants of mothers coming from countries with suboptimal vaccination programs. We describe a case of CRS in a full-term baby girl born to a foreign mother who documented perinatal antibodies against rubella. The baby had the classical abnormalities seen in infants with CRS include congenital cardiac and ocular anomalies. The diagnosis was confirmed by positive rubella serology in both infant and mother. Vaccination is the only known prophylactic measure for congenital rubella syndrome.

References

Kimberlin DW, Brady MT, Jackson MA, Long SS, editors. Red Book: 2018 Report of the Committee on infectious diseases. 31st ed. Itasca: American Academy of Pediatrics; 2018:705-11.

Adam O, Makkawi T, Kannan A, Osman M. Seroprevalence of rubella among pregnant women in Khartoum state, Sudan. Eastern Mediterranean Health Journal. 2013;9(9):812-5.

Fang J, Agrawal A, Gowtham S, Jalazo E, Park HJS, Valsamakis A, et al. Case Report: Congenital rubella syndrome: a rare but persistent concern in the United States. Journal of Perinatology. 2013;33:899-902.

Lambert N, Strebel P, Orenstein W, Icenogle J, Poland GA. Rubella. Lancet. 2015;385:2297-307.

Adam O, Ali A, Hübschen J, Muller C. Identification of congenital rubella syndrome in Sudan. BMC Infectious Diseases. 2014;(14):305-9.

Athira PS, Simon H, Sivakumar T. Congenital rubella syndrome- a case report. International Journal of Research and Review. 2019;6(11):421-4.

Nazme N, Hussain M, Das A. Congenital rubella syndrome- a major review and update. Delta Med Col J. 2015;3(2):89-95.

Tiwari C, Sandlas G, Jayaswal S, Shah H. Hydrocephalus in congenital rubella syndrome: a case report. J Immunol Infect Dis. 2014;2(1):1-4.

Pramila B, Mohan MB, Kavitha K. Congenital rubella syndrome. TNOA J Ophthalmic Sci Res. 2018;56:254-6.

Chauhan N, Sen MS, Jhanda S, Grover S. Psychiatric manifestations of congenital rubella syndrome: A case report and review of the literature. J Pediatr Neurosci. 2016;11:137-9.

Dasgupta S, Shakeel T, Roy RC. TORCH-screening in pediatric cataract revisited: A North Indian tertiary care centre study. Indian J Ophthalmol. 2020;68:769-75.

Hübschen J, Bork S, Brown K, Mankertz A, Santibanez S, Mamou MB, et al. Challenges of measles and rubella laboratory diagnostic in the era of elimination. Clinical Microbiology and Infection. 2017;23:511-5.

Singh A, Narula S, Kareem H, Bevasia T. An infant with congenital rubella syndrome in developing India. BMJ Case Reports. 2017;BCR2017:221665.

Leung A, Hon KL, Leong KF. Rubella (German measles) revisited. Hong Kong Med J. 2019;25:134-41.

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Published

2020-09-21

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Section

Case Reports