Nutrition status and outcome in children with acute pancreatitis


  • Laxmi K. Bharti Department of Pediatric Gastroenterology, SGPGI, Lucknow, Uttar Pradesh, India
  • Jai Kishun Department of Biostatistics and Health Informatics, SGPGI, Lucknow, Uttar Pradesh, India
  • Basant Kumar Department of Pediatric Surgery, SGPGI, Lucknow, Uttar Pradesh, India



Acute pancreatitis, Body mass index, Children, Nasojejunal, Nutrition


Background: AP (Acute Pancreatitis) in children is being more and more diagnosed across the world and developing nation like India. This may be because of multiple factors like better health sector developments, change in dietary and social lifestyle changes due to fast improving economy. There are lots of unknown factors also leading to increase in incidence of AP in children in developing nations like India.

Methods: Five-year retrospective data of AP patients admitted Paediatric Gastroenterology department extracted. Data of 63 children collected in five years from 2012 to 2016. Anthropometric data, feeding details, liver function test (LFT) data recorded. Anthropometric data analysed with IAP growth charts. Data entered in excel sheet of window 10. Appropriate statistical data used for analysis of variables.

Results: Majority of children of AP were 11-15 years age group. In 63 patients, 28 (44.4%) were undernourished, 23 (36.5%) having normal BMI, 9 (14.3%) were overweight and 3 (4.8%) were obese. Nasojejunal feeding was associated mostly in patients with severe AP. LFT were deranged mostly in cases of severe AP.

Conclusions: Overweight, obese and also undernourished children were having more severe AP. Children on nasojejunal feeding (NJ) were mostly having severe AP.


Lopez MJ. The changing incidence of acute pancreatitis in children: a single-institution perspective. J Pediatr. 2002;140:622-4.

Morinville VD, Barmada MM, Lowe ME. Increasing incidence of acute pancreatitis at an American pediatric tertiary care center: is greater awareness among physicians responsible? Pancreas. 2010;39:5-8.

Lowe M, Morinville V. Acute pancreatitis in children. The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery. Malden, Massachusetts: Blackwell Publishing; 2008: 184-192.

Anderson PM, Butcher KE. Childhood Obesity: Trends and Potential Causes. Spring 2006;16(1):19-45.

Weihrauch-Blüher S, Wiegand S. Risk Factors and Implications of Childhood Obesity. Curr Obes Rep. 2018 Dec;7(4):254-59.

Papachristou GI, Papachristou DJ, Avula H, Slivka A, Whitcomb DC. Obesity increases the severity of acute pancreatitis: performance ofAPACHE-O score and correlation with the inflammatory response. Pancreatol. 2006;6(4):279-85.

Martinez J, Johnson C, Sanchez-Paya J, De Madaria E, Robles-Diaz G, Perez-Mateo M. Obesity is a definitive risk factor of severity and mortality in acute pancreatitis: an updated meta-analysis. Pancreatol. 2006;6(3):206-9.

Navina S, Acharya C, DeLany JP, Orlichenko LS, Baty CJ, Shiva SS, et al. Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity. Sci Translat Med. 2011 Nov 2;3(107):107ra110.

Wu BU, Conwell DL. Acute pancreatitis part II: approach to follow-up. Clin Gastroenterol Hepatol. 2010;8:417-22.

Abu-El-Haija M, Lin TK, Palermo J. Update to the management of pediatric acute pancreatitis: highlighting areas in need of research. J Pediatr Gastroenterol Nutr. 2014 Jun 1;58(6):689-93.

Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of childhood and adult obesity in the United States, 2011-2012. Jama. 2014 Feb 26;311(8):806-14.

Khadilkar VV, Khadilkar AV. Revised Indian Academy of Pediatrics 2015 Growth Charts for Height, Weight and Body Mass Index for 5-18-year-old Indian Children. Indian J Endocrinol Metab. Jul-Aug 2015;19(4):470-6.

International Institute for Population Sciences. National Family Health Survey (NFHS-4) 2015–16 India. International Institute for Population Sciences (IIPS) and ICF. 2017;2017.

Pandey RM, Madhavan M, Misra A, Kalaivani M, Vikram NK, Dhingra V. Centiles of anthropometric measures of adiposity for 14- to 18-year-old urban Asian Indian adolescents. Metab Syndr Relat Disord. 2009;7:133-42.

Naval Chandra BA, Venkatesh K, Teja GD, Katkam SK. Prevalence of childhood obesity in an affluent school in Telangana using the recent IAP growth chart: A pilot study. Indian J Endocrinol Metab. 2019 Jul;23(4):428-32.

Ashton D. Food advertising and childhood obesity. J R Soc Med. 2004 Feb; 97(2):51-2.

Jazrawi SF, Barth BA, Sreenarasimhaiah J. Efficacy of endoscopic ultrasound-guided drainage of pancreatic pseudocysts in a pediatric population. Dig Dis Sci. 2011;56:902-8.

Patty I, Kalaoui M, Al-Shamali M, Al-Hassan F, Al-Naqeeb B. Endoscopic drainage for pancreatic pseudocyst in children. J Pediatr Surg. 2001;36:503-5.






Original Research Articles