Radiological profile of neurocysticercosis in children in North India
DOI:
https://doi.org/10.18203/2349-3291.ijcp20160150Keywords:
CECT, Colloidal stage, Electroencephalography, NeurocysticercosisAbstract
Background: Neurocysticercosis (NCC) is defined as an infection of the brain and its coverings by tapeworm (Taenia solium). NCC is a leading cause of acquired epilepsy worldwide. There are few studies in children with neurocysticercosis.
Methods: 61 patients were selected for study (July 2012 to December 2013.) who met the definitive or probable diagnosis of neurocysticercosis as per the criteria for neurocysticercosis. Contrast enhanced CT scan (CECT) of the head was done in all 61 children.
Results: All 61 patients present with seizures. Focal seizures present in 34 (55.7%) children, were more common than generalized seizures. CECT brain single lesion was present in 57 (93.4%) patients. Most common site was parietal lobe in 38 (55.7%). In this study in CECT brain Colloidal stage, observed among 40 (65.5%) was the most common stage of NCC. Among cases, 30 (49.2%) of the patients, the size of lesion in CECT brain was 5-10 mm, in 20 (32.8%) it was <5 mm. However, the Size of lesion in CECT Brain was >10 mm in only 11 (18%).There was no statistical difference between the groups in Size of lesion in CECT Brain.
Conclusions: Majority of patients with NCC presented with clusters of symptoms comprising of seizure, headache and vomiting. Focal seizures were more common type of seizures .CECT brain evolved as the most useful modality of screening of patients with NCC. Most of the patients had solitary lesion on CECT brain. Colloidal stage was the most common stage on CECT Brain. Most of lesion involved parietal lobe.
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References
Cameron ML, Durack DT. Helminthic infections. In: W.M. Scheld, R.J. Whitley and D.T. Durack, eds. Lippincott's Infections of the Central Nervous System. 2nd edn. Philadelphia: Raven Publishers. 1997:845-78.
Garcia HH, Gonzalex AE, Evans CA, Gilman RH. Cysticercosis Working Group in Peru: Taenia solium cysticercosis. Lancet. 2003;362:547-56.
Carpio A. Neurocysticercosis: an update. Lancet Infect Dis. 2002;2:751-62.
Del Brutto OH, Santibanez R, Noboa CA, Aguirre R, Diaz E, Alarcon TA. Epilepsy due to neurocysticercosis: analysis of 203 patients. Neurology. 1992;42:389-92.
Kalra V, Sethi A. Childhood neuro-cysticercosis-epidemiology, diagnosis and course. Acta Pediatr Jpn. 1992;34:365-70.
Del Brutto OH, Wadia NH, Dumas M, Cruz M, Tsang VC, Schantz PM. Proposal of diagnostic criteria for human cysticercosis and neurocysticercosis. J Neurol Sci. 1996;142:1-6.
Rajshekhar V. Etiology and management of single small CT lesions in patients with seizures: understanding a controversy . Act a Neurol Scand. 1991;84:465-70.
Patil TB, Paithankar MM. Clinico-radiological profile and treatment outcomes in neurocysticercosis: A study of 40 patients. Anals of tropical medicine and public health. 2010;3(2):58-63.
Chaurasia RN, Garg RK, Agarwall A, Kohli N, Verma R, Singh MK, et al. Three day albendazole therapy in patients with a solitary cysticercus granuloma: a randomized double blind placebo controlled study. Southeast Asian J Trop Med Public Health. 2010;41:517-25.
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