Study of clinical profile, risk factors of acute kidney injury in children admitted in pediatric intensive care unit at tertiary health care centre

Harsha S.; Gonesh N. Mevundi

doi:10.18203/2349-3291.ijcp20203159

Authors

Harsha S. Department of Pediatrics, Mahadevappa Rampure Medical College Kalaburgi, Karnataka, India
Gonesh N. Mevundi Department of Pediatrics, Mahadevappa Rampure Medical College Kalaburgi, Karnataka, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20203159

Keywords:

Acute kidney injury, Incidence, Pediatric intensive care unit, Risk factors, Ventilation

Abstract

Background: Acute kidney injury (AKI) is an important condition in hospitalized patients, associated with adverse short- and long-term outcomes. Objective of this study was to determine the clinical profile of acute kidney injury in pediatric ICU (Basaveshwar Teaching and General Hospital, Sangameshwar Hospital, Kalaburagi).

Methods: This study was conducted in all patients within the age group of 1 month to 18 years admitted in the PICU (pediatric intensive care unit) at Basaveshwar teaching and General hospital and Sangameshwar hospital attached to Mahadevappa Rampure medical college during a period from December 2015 to May 2017.

Results: Incidence of AKI was 6.9% in pediatric intensive care unit. The median age of boys and girls were 4.56±3.84 and 4.49±4.01 respectively. Hypotension and need for ventilation were significant risk factors for AKI (p<0.001). The median admission serum creatinine value in AKI patients was 2.91±2.48 mg/dL. In the present study, the median duration of PICU and Hospital stay was 9.98±7.27 in AKI group compared to7.41±5.62 days in non-AKI group (p<0.001).

Conclusions: It was concluded that Incidence of AKI was 6.9% in pediatric intensive care unit. The mean and SD of age of boys and girls were 4.56±3.84 and 4.49±4.01 respectively. Hypotension and need for ventilation were significant risk factors for AKI.

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References

Srinivastav RN, Bagga A. Acute kidney injury: Indian Pediatrics; 5th ed. 2011;235.

Palmieri T, Lavrentieva A, Greenhalgh D. An assessment of acute kidney injury with modified RIFLE criteria I pediatric patients with severe burns. Intensive Care Med. 2009;35:2125-9.

Srinivasa S, Reshmavathi V. Incidence and etiology of acute kidney injury in children in admitted to PICU. Using PRIFLE criteria. Curr Pediatr Res. 2016;20(1 and 2):1-6.

Krishnamurthy S, Narayanan P, Prabha S, Mondal N, Mahadevan S, Biswal N, et al. Clinical profile of acute kidney injury in a pediatric intensive care unit from Southern India: A prospective observational study. Indian Society Crit Care Med. 2013;17(4):207.

Rama G. Study of acute kidney injury in children: its aetiology, clinical profile and outcome. J Evid Bas Med Healthcare. 2015;2(11):1577-85.

Naik S, Sharma J, Yengkom R, Kalrao V, Mulay A. Acute kidney injury in critically ill children: Risk factors and outcomes. Indian Society Crit Care Med. 2014;18(3):129.

Prabhakar TS, Deepthi G, Rekha R, Rao NV. Study of acute kidney injury in children admitted to pediatric intensive care unit. Int J Food Nutrit Sci. 2015;4(3):115.

Gupta S, Sengar GS, Meti PK, Lahoti A, Beniwal M, Kumawat M. Acute kidney injury in pediatric intensive care unit: Incidence, risk factors, and outcome. Indian J Crit Care Med. 2016;20(9):526-9.

Mehta P, Sinha A, Sami A, Hari P, Kalaivani M, Gulati A, et al. Incidence of acute kidney injury in hospitalized children. Indian Pediatr. 2012;49(7):537-42.

Li S, Krawczeski CD, Zappitelli M, Devarajan P, Thiessen-Philbrook H, Coca SG, et al. Incidence, risk factors, and outcomes of acute kidney injury after pediatric cardiac surgery: a prospective multicenter study. Crit Care Med. 2011;39(6):1493-9.