An observational study of early neonatal outcome in babies born to mothers with pregnancy induced hypertension

Ramya C., Rathna Kumari, Charishma Chitneni


Background: Hypertensive disorders in pregnancy are a major cause of maternal morbidity and mortality accounting for 15-20% of maternal deaths worldwide. In India the incidence of preeclampsia is reported to be 8-10 percent of the pregnancies objective of this study was to with the above background, this study was carried out to study early neonatal outcome in babies born to PIH mothers, Measure the adverse neonatal outcomes in the early neonatal period and compare the mode of delivery between control group and PIH group.

Methods: A total of 58 neonates born to mothers diagnosed having gestational hypertension, preeclampsia, eclampsia were taken as tests (group A), and 100 apparently healthy newborns born to normotensive mothers were enrolled as controls (group B) and followed up to 1st week of life. The outcome measures were compared between groups in terms of mode of delivery, preterm delivery, birth weight, APGAR score, intra uterine growth retardation, early neonatal complications.

Results: In group A, 33 had LBW (56.89%) and in group B 18 had LBW (18%). The incidence of preterm deliveries in group A was higher as compared to group B (A- 43.10%, B-17%, p value <0.05). Babies born to PIH mothers had an increased incidence of IUGR, as compared to group B.

Conclusions: PIH is one of the major causes of maternal, fetal and early neonatal morbidity and mortality. In this study authors found that risk of LBW, preterm delivery, NICU admission and IUGR in babies born to PIH mothers statistically significant. Early detection of high-risk individual by well trained personnel and timely referral to advanced tertiary center is necessary in bringing down the maternal and neonatal morbidity and mortality.


Intra uterine growth retardation, Low birth weight, Pre-eclampsia, Pregnancy induced hypertension

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John p. Clotherty. Eric C. EInchenwald. Ann. R. Stark, Manual of Neonatal care, 6th ed. Lippincott Williams and Wilkins, New Delhi, 2008:22

Srinivas SK, Edlow AG, Neff PM, Sammel MD, Andrela CM, Elovitz MA. Rethinking IUGR in preeclampsia: dependent or independent of maternal hypertension?. J Perinatol. 2009;29(10):680‐4.

Avery's diseases of the new born. H. William Tanesh, Roberts A. Ballard (eds) 8th ed. Elsevier, New Delhi; 2005:99-105.

American College of Obstetricians and Gynecologists. Diagnosis and management of pre-eclampsia and Eclampsia. Practice Bulletin No.33, Washington, DC: ACOG. 2002;99(1):159-67.

Australian Society for the study of Hypertension in pregnancy, Consensus statement on Management of Hypertension in Pregnancy. Executive Summary. Med. J. Aust. 1993;158:700-2.

Spinillo Aa, Lasci A. Two-year infant neurodevelopment outcome after expectant management and indicated preterm delivery in hypertension pregnancy Acta J Obstet Gynecol. 1994;73;625-9.

Chari RS Frienman SA. Schiff E, Frangeh AY, Sibai BM. Is fetal neurological and physiological development accelerated in preeclamsia? Am J Obstet Gynaecol. 1996:174:829-32.

Gofton EN, Capewell V, Natale R, Gratton RJ. Obstetrical intervention rates and maternal and neonatal outcomes of women with gestational hypertension. Am J Obstet Gynecol. 2001;185(4):798-803.

Bahl NJJ, Parekh P. Perinatal outcome in pregnancy induced hypertension; Indian Pediatr. 2001;38:174-8.

Solangeregina, de Oliveira SMJV, Kimura AF. Pregnancy – induced hypertension and neonatal outcome, actapul. Enfem, Jan /Mar; 2008:21.

Yücesoy G, Özkan S, Bodur H, Tan T, Çalışkan E, Vural B, et al. Maternal and perinatal outcome in pregnancies complicated with hypertensive disorder of pregnancy: a seven year experience of a tertiary care center. Arch Gynec Obstet. 2005;273(1):43-9.

Yadav S Saxena u Yadav R Gupta S. Hypertensive disorders of Pregnancy and maternal and fetal outcome. J Indian Med. Assoc. 1997;95(10);548-51.

Bangal VB, Giri PA, Mahajan AS. Maternal and foetal outcome in pregnancy induced hypertension: a study from rural tertiary care teaching hospital in India. Int J Biome Res. 2011;2(12):595‐9.

Chang JJ, Muglia LJ. Association of early onset preeclamsia in first pregnancy with normotensive second pregnancy outcomes; a population-based study. BJOG. 2010;117:946-53.

Masoura S, Kalogiannidis I, Margioula-Siarkou C, Diamanti E, Papouli M, Drossou-Agakidou V, et al. Neonatal outcomes of late preterm deliveries with pre-eclampsia. Minerva Ginecol. 2012;64:109-15.

Ara J, Jamal M, Sultana N. Perinatal outcome in pregnancy induced hypertensive mothers. Pak. Armed Forces Med J. 2004;54(1):76-8.

Aslan H, Gul A, Cebeci A. Neonatal outcome in pregnancies after preterm delivery for HELLP syndrome. Gynecol. Obstet. Invest. 2004;58:96-9.

Carvatha MA. Faundes. Pregnancy-induced hypertension and hyaline membrane disease. Int J Obstetrics Gynecol. 1997:58(2);197-202.

Shweta A, Krishna A, Perinatal Outcome in Growth Retarted Babies Born to Normotensive and Hypertensive Mothers: A Prospective Study, Peoples’s. J Sci Res. 2012;5(1):24-8.

Bhaumik S, Ghosh S, Haldar KK, Mitra PK, Manna B. Risk of early onset Neonatal septicemia in babies born to mother with pre-eclampsia. Indian Paediatr. 2000:37(7):775-9.

Zafar H, Naz M, Fatima U, Irshad F. Frequency of IUGR in pregnancy induced hypertension. JUMDC. 2012;3(2):8-13.

Wolde Z, Segni H, Woldie M. Hypertensive disorders of pregnancy in Jimma University specialized hospital. Ethiop J Health Sci. 2011;21(3):147-54.

Dudell GG, Jain L. Hypoxic respiratory failure in the late preterm infant. Clin Perinatol. 2006;33(4):803-30.

Jain L. Respiratory morbidity in late-preterm infants: prevention is better than cure. Am J Perinatol. 2008:25(2):75-8.