Published: 2020-05-22

Pattern and prevalence of metabolic syndrome in obese adolescents aged 10-18 years: a community based study

K. Jothilakshmi, Vadivel Vinoth, Suvetha Kannappan


Background: The prevalence and magnitude of childhood obesity is increasing in pediatric age group. Incidence of metabolic syndrome is high among obese children and adolescents leading to increased risk of cardiovascular morbidity in long term. For this reason, recognition of metabolic syndrome in obese children is of great importance.

Methods: This study was a cross-sectional study carried out among children aged 10-18 years from both urban and rural schools in Coimbatore. Children were screened, sample for metabolic studies collected after consent and analyzed.

Results: Total 1582 children in the age group of 10-18 years were screened. 300 children were recruited. Among the studied group, 19.3% were overweight, 30.7% were obese. Metabolic syndrome was present in 55.1% of obese and overweight children. Hyperinsulinemia was present in 30% of obese children.

Conclusions: This study done in adolescent school children showed a strong association between obesity and early onset of metabolic syndrome. Early intervention with lifestyle modifications is strongly recommended to prevent long term cardiovascular morbidity.



Adolescent children, Metabolic syndrome, Obesity

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Misra A, Shah P, Goel K, Hazra DK, Gupta R, Seth P, et al. The high burden of obesity and abdominal obesity in urban Indian schoolchildren: a multicentric study of 38,296 children. Ann Nutr Metab. 2011;58(3):203-11.

Andrabi SM, Bhat MH, Andrabi SR, Kamili MM, Imran A, Nisar I, et al. Prevalence of metabolic syndrome in 8–18-year-old school-going children of Srinagar city of Kashmir India. Indian J Endocrinol Metab. 2013 Jan;17(1):95.

Singh N, Parihar RK, Saini G, Mohan SK, Sharma N, Razaq M. Prevalence of metabolic syndrome in adolescents aged 10-18 years in Jammu, J and K. Indian J Endocrinol Metab. 2013 Jan;17(1):133.

Bhalavi V. International Journal of Biomedical Research. Age (years).;15(15):159.

Reaven GM. Banting Lecture 1988: role of insulin resistance in human disease. Diab. 1988;37:1595-607.

Levitt NS, Lambert EV. The foetal origins of the metabolic syndrome -a South African perspective. Cardiovasc J S Afr. 2002;13:179-80.

Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J, et al. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. Jama. 2002 Dec 4;288(21):2709-16.

Weiss R, Dziura J, Burgert TS, Tamborlane WV, Taksali SE, Yeckel CW, et al. Obesity and the metabolic syndrome in children and adolescents. N Engl J Med. 2004 Jun 3;350(23):2362-74.

International Obesity Task Force. Available at: http://www., for Saudi, Canada, South Africa, Australia and NZ estimates. Accessed 23 December 2019.

Chakraborty P, Dey S, Pal R, Kar S, Zaman FA, Pal S. Obesity in Kolkata children: Magnitude in relationship to hypertension. J Natural Sci Bio Med. 2012;2:101-6.

Shah B, Anand K, Joshi P, Mahanta J, Mohan V, Thankappan K, et al. Report of the Surveillance of Risk Factors of Non-communicable Diseases (STEPS 1 and 2) From Five Centers in India – WHO India – ICMR initiative. New Delhi.

Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;364(9468):1415-28.

Goodman E, Daniels SR, Morrison JA, Huang B, Dolan LM. Contrasting prevalence of and demographic disparities in the world health organization and national cholesterol education program adult treatment panel III definitions of metabolic syndrome among adolescents. J Pediatr. 2004;4(59): 445-51.

Tailor AM, Peeters PH, Norat T, Vineis P, Romaquera D. An update on the prevalence of the metabolic syndrome in children and adolescents. Int J Pediatr Obes. 2010;5(3):202-13.

Cameron AJ, Shaw JE, Zimmet PZ. The metabolic syndrome: prevalence in worldwide populations. Endocrinol Metab Clin North Am. 2004;33(2):351-75.

Sangun Ö, Dündar B, Köşker M, Pirgon Ö, Dündar N. Prevalence of metabolic syndrome in obese children and adolescents using three different criteria and evaluation of risk factors. J Clini Res Pediatr Endocrinol. 2011 Jun;3(2):70.

Invitti C, Maffeis C, Gilardini L, Pontiggia B, Mazzilli G, Girola A, et al. Metabolic syndrome in obese Caucasian children: prevalence using WHO-derived criteria and association with nontraditional cardiovascular risk factors. Inter J Obesity. 2006 Apr;30(4):627-33.

Jacob AS, Reetha G. Prevalence of metabolic comorbidities in obese children. Int J Contemp Pediatr. 2017;4(4):1450-5.

Singh R, Bhansali A, Sialy R, Aggarwal A. Prevalence of metabolic syndrome in adolescents from a north Indian population. Diab Med. 2007;24:2.

Atabek ME, Pirgon O, Kurtoglu S. Prevalence of metabolic syndrome in obese Turkish children and adolescents. Diab Res Clini Pract. 2006 Jun 1;72(3):315-21.