Study of intracranial structural lesions diagnosed by computed tomography among children with unprovoked seizure disorder


  • Priyanka Choudhary Department of Community Medicine, Pt. B.D Sharma PGIMS, Rohtak, Haryana, India
  • Amit Kumar Mital Department of Pediatrics, BPSGMC for women, Khanpurkalan, Sonepat, Haryana, India
  • Sheela Sinha Department of Pediatrics, Patna Medical College, Patna, Bihar, India



Children, Computed tomography brain, Intracranial structural lesion, Unprovoked seizure


Background: Seizures are the most common pediatric neurological disorder. The objectives were to know the prevalence and types of intracranial structural lesions diagnosed by Computed Tomography in children with unprovoked seizures.

Methods: It is hospital based cross-sectional study done in Patna Medical College, India from August 2005- July 2007. All patients aged 6 months to 12 years admitted in pediatrics department with at least 2 episodes of unprovoked seizures were undergone Computed Tomography brain.

Results: Out of total 112 patients admitted, 66.1% had abnormal CT scan. Prevalence of abnormal CT scan increased with advancing age and significant, with maximum percentage found in age group 10-12 years (43.2%). Males had more seizures and intracranial lesion than females but this association was statistically non-significant. 65.2% had generalized seizure and 34.8% had partial seizure. Among patients with abnormal CT scan, generalized seizure (70.3%) and partial seizure (29.7%).The commonest  probable diagnosis was tuberculoma (47.3%) followed by neurocysticercosis (25.7%) and brain abscess (4%). Other were atrophy, gliosis and hydrocephalus, 2.5% each; arachnoid cyst, extradural hematoma, sturge weber syndrome, tuberous sclerosis, infarct, hemiatrophy, caudate lobe hemorrhage, basal ganglia calcification, corpous callosum agenesis, 1.35% each.

Conclusions: Inflammatory granuloma is the leading cause of unprovoked seizure in this part of the country. Every seizure case should undergo a CT scan examination. Preventive measures can be applied for tuberculoma and NCC so as to lower down the burden of seizure disorder.


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