Study of spirometry parameters in suspected asthmatic children in a tertiary care hospital

Authors

  • Arpita Mishra Department of Pediatrics, Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India
  • Deepak Ugra Department of Pediatrics, Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India
  • Utpal Kumar Department of Cardiology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20201631

Keywords:

Asthma, Bronchodilator, FEF25-75%, Spirometry

Abstract

Background: Asthma in children is difficult to diagnose due to inability of young children to successfully perform spirometry. However some parameters in the spirometry which are relatively effort independent can be very helpful in confirming the diagnosis of asthma. This study was conducted to find out the most commonly affected spirometry parameter in the suspected cases of childhood asthma.

Methods: Total 56 children were studied between 7 to 18 years who came for outpatient visit or admitted in the paediatric ward and were clinically suspected to be asthmatic based on asthma predictive index. They were subjected to spirometry in our institute. Baseline and post bronchodilator values of spirometry parameters were studied and analysed using standard statistical tests.

Results: Baseline Forced expiratory flow between 25% and 75% of vital capacity (FEF25-75%) was found to be the most commonly affected spirometry parameter in confirming the diagnosis of suspected asthmatics and correlated with the clinical diagnosis of childhood asthma.

Conclusions: FEF25-75% can aid in confirming the diagnosis of suspected asthmatic children who are otherwise not treated as asthmatics and remain undiagnosed in view of not meeting the established spirometry criteria for asthma due to poor performance and ignorance of looking at this important and effort independent parameter.

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References

Asher I, Pearce N. Global burden of asthma among children. Inter J Tuberculosis Lung Dis. 2014; 18(11):1269-78.

Castro-Rodriguez J. The Asthma Predictive Index: early diagnosis of asthma. Curr Opinion Allergy Clini Immunol. 2011; 11(3):157-61.

Rao DR, Gaffin JM, Baxi SN, Sheehan WJ, Hoffman EB, Phipatanakul W. The utility of forced expiratory flow between 25% and 75% of vital capacity in predicting childhood asthma morbidity and severity. J Asthma. 2012 Aug 1; 49(6):586-92.

Miller MR, Hankinson JA, Brusasco V, Burgos F, Casaburi R, Coates A, et al. Standardisation of spirometry. Europ Respirat J. 2005; 26(2):319-38.

Galant SP, Morphew T, Amaro S, Liao O. Value of the bronchodilator response in assessing controller naïve asthmatic children. J Pediatr. 2007 Nov 1; 151(5):457-62.

Kliegman R, Stanton B, St. Geme J, Schor N. Nelson textbook of pediatrics. 20th ed. Philadelphia: Elsevier; 2016:1098-1099.

Ciprandi G, Capasso M, Tosca M, Salpietro C, Salpietro A, Marseglia G, et al. A forced expiratory flow at 25-75% value< 65% of predicted should be considered abnormal: a real-world, cross-sectional study. Allergy Asthma Proceedings. 2012;33(1):5

Marseglia GL, Cirillo I, Vizzaccaro A, Klersy C, Tosca MA, La Rosa M, et al. Role of forced expiratory flow at 25-75% as an early marker of small airways impairment in subjects with allergic rhinitis. Allergy Asthma Proceedings. 2007;28(1).

Kanchongkittiphon W, Gaffin JM, Kopel L, Petty CR, Bollinger ME, Miller RL, et al. Association of FEF25%–75% and bronchodilator reversibility with asthma control and asthma morbidity in inner-city children with asthma. Ann Allergy, Asthma Immunol. 2016 Jul 1;117(1):97-9.

Levy ML, Quanjer PH, Rachel B, Cooper BG, Holmes S, Small IR. Diagnostic Spirometry in Primary Care: Proposed standards for general practice compliant with American Thoracic Society and European Respiratory Society recommendations. Pri Care Respiratory J. 2009 Sep; 18(3):130-47.

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Published

2020-04-24

How to Cite

Mishra, A., Ugra, D., & Kumar, U. (2020). Study of spirometry parameters in suspected asthmatic children in a tertiary care hospital. International Journal of Contemporary Pediatrics, 7(5), 1023–1027. https://doi.org/10.18203/2349-3291.ijcp20201631

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Original Research Articles