Congenital chylothorax: a rare entity

Prachi Gandhi, Sushma Malik, Nilesh N. Jamkar, Vinaya A. Singh, Poonam Wade


Pleural effusions in a neonate are generally congenital in about one third of the cases and acquired in the remaining two thirds. Congenital isolated pleural effusion is rare. It has an incidence of approximately 1 in 12000 to 1 in 15000 pregnancies. Chylothorax is the most common cause of neonatal congenital pleural effusion. Incidence of congenital chylothorax is 1 in 8600 to 1 in 10000 deliveries with a male to female ratio of 2:1. It poses both a diagnostic as well as therapeutic challenge to the neonatologist. Authors hereby present a rare case of congenital chylothorax which was medically managed and discharged. The neonate responded well to octreotide and medium chain triglyceride (MCT)-diet and was discharged without any complications.


Chylomicron, Congenital chylothorax, Congenital pleural effusion, Octreotide

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Wiener-Kronish JP, Berthiaume Y, Albertine KH. Pleural effusions and pulmonary edema. Clin Chest Med. 1985;6(3):509-19.

Taeusch HW, Ballard RA, Gleason CA. Avery’s diseases of the newborn. 8th ed. Philadelphia: Elsevier Saunders; 2005:682.

Rocha G, Fernandes P, Rocha P, Quintas C, Martins T, Proenca E. Pleural effusions in the neonate. Acta Paediatr. 2006;95(7):791-8.

Rocha G. Pleural effusions in the neonate. Curr Opin Pulm Med. 2007;13(4):305-11.

Al-Tawil K, Ahmed G, Al-Hathal M, Al-Jarallah Y, Campbell N. Congenital chylothorax. Am J Perinatol. 2000;17(3):121-6.

De Beer HG, Mol MJ, Janssen JP. Chylothorax. Neth J Med. 2000;56(1):25-31.

Dendale J, Comet P, Amram D, Lesbros D. Le chylothorax de découverteanténatale. Arch Pediatr.1999;6(8):867-71.

Dubin PJ, King IN, Gallagher PG. Congenital chylothorax. Curr Opin Pediatr. 2000;12(5):505-9.

Van Straaten HL, Gerards LJ, Krediet TG. Chylothorax in the neonatal period. Eur J Pediatr. 1993;152(1):2-5.

Rocha G. Pleural effusions in the neonate. Curr Opin Pulm Med.2007;13(4):305-11.

Van Aerde J, Campbell AN, Smyth JA, Lloyd D, Bryan MH. Spontaneous chylothorax in newborns. Am J Dis Child. 1984;138(10):961-4.

Gleason CA, Devaskar SU, Beghetti. Surgical disorder of the chest and airways. Avery’s Diseases of the newborn. 9th Edn. Elsevier; 2012:683.

Conservative management of postsurgical chylothorax with octreotide. Asian Cardiovasc Thorac Ann. 2005;13:222-4.

Das A, Shah P. Octreotide for the treatment of chylothorax in neonates. Cochrane Database Syst Rev. 2010;(9):CD006388.