Clinical profile of dengue fever in children admitted in a district hospital of South India


  • Ramaswami Muthusamy Department of Pediatrics, Government District Headquarters Hospital, Namakkal, Tamil Nadu, India
  • Palanivel Sengottaiyan Department of Pediatrics, Government District Headquarters Hospital, Namakkal, Tamil Nadu, India



Children, Clinical profile, Dengue fever, Diagnosis


Background: To assess the clinical profile of dengue fever in children.

Methods: In this Prospective observational study 110 patients who admitted in Government District Headquarters Hospital, Namakkal between 1st August 2019 to 31st December 2019 were included. Those patients with confirmed dengue, with IgM dengue antibody positive were included in this study. Detailed history was taken, and clinical examination was performed, and laboratory investigations were done.

Results: In this study 110 patients were studied, majority were males. Fever was present in 100% of patients followed by headache, myalgia. The common signs and symptoms of dengue infection were fever, headache, body ache, retro-orbital pain, bleeding manifestations, and rash in 100%, 97.27%, 92.72%, 77.27%, 8.12%, and 60.90%, respectively. In 90 cases platelet count was less than 100,000/cumm of which bleeding manifestation was found in 9 patients. Pleural effusion and ascites were observed in 25 and 15 cases respectively. Hepatomegaly was noted in 19 cases and splenomegaly in 10. Leucopenia was present in 52 cases whereas raised liver enzymes were present in 51 cases. The mortality rate was 0.9%.

Conclusions: Dengue epidemic has increased in recent past probably due to unplanned urbanization with rapid construction activities, unhygienic condition and poor sanitation facilities contributing fertile breeding soil for mosquitoes. Early diagnosis and management can decrease mortality and morbidity of illness. Platelet transfusions have little role in management of dengue patients.


CDC. Imported dengue-United States, 1997 and 1998. Morb Mortal Wkly Rep. 2000;49:248-5.

Engelthaler DM, Fink TM, Levy CE, Leslie MJ. The reemergence of Aedes aegypti in Arizona. Emerg Infect Dis. 1997;3:241-2.

Gupta N, Srivastava S, Jain A, Chaturvedi UC Dengue in India. Ind J Med Res. 2012;136(3):373-90.

Wichmann O, Hongsiriwon S, Bowonwatanuwong C, Chotivanich K, Sukthana Y, Pukrittayakamee S. Risk factors and clinical features associated with severe dengue infection in adults and children during the 2001 epidemic in Chonburi, Thailand. Trop Med Inter Health. 2004;9(9):1022-9.

Gubler DJ . Dengue and dengue hemorrhagic fever. Clin Microbiol Rev. 1998;11:480-96.

Gupta P, Khare V, Tripathi S, Nag VL, Kumar R, Khan MY, et al. Assessment of WHO definition of dengue hemorrhagic fever in North India. J Infect Dev Ctries. 2010;4:150-5.

Kumaria R, Chakravarti A. Molecular detection and serotypiccharacterization of dengue viruses by single tube multiplex RT-PCR. Diagn Microbiol Infect Dis. 2005;52(4):311-6.

Chakravarti A, Kumaria R. Ecoepidemiological analysis ofdengue infection during an outbreak of dengue fever, India. Virology J. 2005;2:32;1-7.

Endy TP, Nisalak A, Chunsuttiwat S, Libraty DH, Green S, Rothman AL, et al. Spatial and temporal circulation of dengue virus serotypes: a prospective study of primary school children in Kamphaeng Phet, Thailand. Am J Epidemiol. 2002 Jul 1;156(1):52-9.

Graham RR, Juffrie M, Tan R, Hayes CG, Laksono I, Ma'Roef C, et al. A prospective seroepidemiologic study on dengue in children four to nine years of age in Yogyakarta, Indonesia I. studies in 1995-1996. Am J Trop Med Hyg. 1999 Sep 1;61(3):412-9.

Ahmed S, Arif F, Yahya Y, Rehman A, Abbas K, Ashraf S, et al. Dengue fever outbreak in Karachi 2006--a study of profile and outcome of children under 15 years of age. JPMA. J Pakistan Med Assoc. 2008 Jan;58(1):4.

Mittal H, Faridi MMA, Arora SK, Patil R. Clinicohematological profile and platelet trends inchildren with dengue during 2010 epidemic in North India. Ind J Pediatr. 2012;79(4):467.

Mandal SK, Ganguly J, Sil K, Chatterjee S, Chatterjee K, Sarkar P, et al. Clinical profiles of dengue fever in a teaching hospital of eastern India. Headache. 2013;40:62-16.

Itoda I, Masuda G, Suganuma A, Imamura A, Ajisawa A, Yamada KI, et al. Clinical features of 62 imported cases of dengue fever in Japan. Am J Trop Med Hyg. 2006 Sep 1;75(3):470-4.

Mia MW, Nurullah AM, Hossain A, Haque MM. Clinical and sonographic evaluation of dengue fever in Bangladesh: a study of 100 cases. Dinajpur Med Coll J. 2010;3:29-34.

Kalayanarooj S, Vaughn DW, Nimmannitya S, Green S, Suntayakorn S, Kunentrasai N, et al. Early clinical and laboratory indicators of acute dengue illness. J Infec Dis. 1997 Aug 1;176(2):313-21.

Singh NP, Jhamb R, Agarwal SK, Gaiha M, Dewan R, Daga MK, et al. The 2003 outbreak of Dengue fever in Delhi, India. Headache. 2005;114:61.

Tripathi BK, Gupta B, Sinha RSK, Prasad S, Sharma DK. Experience in adult population in dengue outbreak in Delhi. J Assoc Phys Ind. 1998;46(3):273-6.

Khan AH, Hayat AS, Masood N, Solangi NM, Shaikh TZ. Frequency and clinical presentation of dengue fever at tertiary care hospital of Hyderabad/Jamshoro. J Liaquat Uni Med Health Sci. 2010;9(2):88-94.

Ageep AK, Malik AA, Elkarsani MS. Clinical presentations and laboratory findings in suspected cases of dengue virus. Saudi Med J. 2006;27(11):1711-3.






Original Research Articles