A clinico-etiological evaluation of neonatal seizures in a tertiary care hospital: a prospective cohort study

Kuldeep Kumar Sharma; Shifa Bidhan; Sandeep D. Paimode

doi:10.18203/2349-3291.ijcp20200696

Authors

Kuldeep Kumar Sharma Department of Paediatrics, Military Hospital, Yol, Himachal Pradesh, India
Shifa Bidhan Department of Paediatrics, Military Hospital, Meerut, Uttar Pradesh, India
Sandeep D. Paimode Department of Paediatrics, Military Hospital, Amritsar, Punjab, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20200696

Keywords:

Birth asphyxia, Neonates, Pre-term, Seizures

Abstract

Background: Neonatal seizure is defined as a paroxysmal alteration in neurological function. The diagnosis of neonatal seizures is difficult to establish because of varied etiologies involved. The incidences vary from 1.5-3.7/1000 live births in term babies.

Methods: Hospital based observational Study was conducted from December 1, 2016 till March 31, 2018. Universal sampling technique was followed. 93 neonates fulfilling the inclusion criteria were included in the study after consent from parents.

Results: Present study results showed that 60.2% were males. Pre-term delivery occurred in 12.9% neonates. Most common etiology of neonatal seizures was birth asphyxia with 47.3% followed by metabolic abnormalities 32.3%.

Conclusions: The most common etiology for neonatal seizures was birth asphyxia followed by metabolic abnormalities in which hypoglycaemia was the most common type. A significant association of seizures due to meningitis and metabolic abnormalities was observed with pre-term gestation.

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