Congenital bilateral perisylvian syndrome: a rare cause of epilepsy

Trishalla Sharma, Gauri Chauhan, Tegsimran Duggal, A. K. Bhardwaj


Congenital bilateral perisylvian syndrome (CBPS) is an entity proven or diagnosed on basis of neuroimaging in the form of MRI (Magnetic Resonance Imaging). A case with classical triad of fascio- masticatory diplegia, epilepsy and mental retardation has been seen. We report a case of a 6 years old male child on intermittent treatment for seizures since 6 months presenting to us with abnormal movement, recurrent spitting and drooling of saliva with slurring of speech. Diagnosed on MRI with involvement of perisylvian location in temporal lobe. The etiology of epilepsy was justified and symptomatically treated.


Congenital bilateral perisylvian syndrome, MRI, Epilepsy, Speech

Full Text:



Hyong K. Congenital Bilateral Perisylvian Syndrome: Analysis of the first four reported Korean patients. Journal of Korean Medical Sciences. 1994;9;4:335-40.

Taneja. Congenital Bilateral Perisylvian Syndrome - A Case report. 2016.

Kuzniecky R, Arderman F, Guerrini R. Congenital Bilateral Perisylvian Syndrome – The Study of 31 patients. Lancet. 1993;341:608-12.

Gowda AK, Mane RS, Kumar A. Congenital Bilateral Perisylvian Syndrome: case report and review of literature. J. Clin Neonatal. 2013;2(4):196-8.

Donders J, Mullarkey SK, Allchin J. Congenital Bilateral Perisylvian Syndrome: A case study. Clin Neuropsychol. 2009;23(2):276-85.

Hussain N. Congenital Bilateral Perisylvian Syndrome presenting with intractable seizures, Indian Pediatrics. 2007;44:543-5.

Andrea R. Early prenatal MR Imaging diagnosis of polymicrogyria AJNR. 2004;25:343-6.

Barkovich AJ. Syndromes of bilateral symmetrical polymicrogyria. AJNR Am J Neuroradiol. 1999;20(10):1814-21.

Margari L, Pressci A. Congenital Bilateral Perisylvian Syndromewith partial epilepsy. Brain Dev. 2005;27:53-7.