Mortality profile in pediatric malignancies: a 11 year retrospective study
DOI:
https://doi.org/10.18203/2349-3291.ijcp20195750Keywords:
Childhood cancers, Febrile neutropenia, Mortality, SepsisAbstract
Background: Malignancy is one of the leading causes of childhood deaths in developed nations while diarrheal and respiratory infections continue to compete in many developing nations. Since the state of Goa, has health statistics comparable to the western world, an attempt has been made to look at the childhood cancer mortality in proportion to overall deaths in the only tertiary care hospital in the state
Methods: In the absence of a population registry, information was obtained from the hospital mortality statistics during the period from January 2007 to December 2017.
Results: A total of 118 cancer deaths were seen over a period of 11 years with a male/female ratio of 1.34:1. The proportion of cancer deaths to total deaths due to any cause, per year was 11.9%. Most of the deaths were noted in the 1-10 years age group (53.4%) with maximum deaths seen in hematological malignancies (50.8%).Though sepsis was the immediate cause of death in 42(35.6%), a significant drop was noted in last 5 years wherein it was observed to fall from 22.8% in the initial 6 years to 12.7% in the latter 5 year period.
Conclusions: Proportion of cancer related deaths were seen to reduce over the study period with a significant drop, in sepsis, as the major cause. Simple measures to control sepsis may help to reduce cancer mortality.
References
Bashar MA, Thakur JS. Incidence and Pattern of Childhood Cancers in India: Findings from Population-based Cancer Registries. Ind J Med Paediatr Oncol. 2017;38(2):240-1.
Summary-Report on Causes of Death: 2001-2003 in India. Available at: http://www.censusindia.gov.in/Vital_Statistics/Summary_Report_Death_01_03.pdf. Accessed on 24 Sep 2013.
Gupta S, Morris SK, Suraweera W, Aleksandrowicz L, Dikshit R, Jha P. Childhood Cancer Mortality in India: Direct Estimates from a Nationally Representative Survey of Childhood Deaths. J Glob Oncol. 2016;2(6):403-11.
Kusumakumary P, Jacob R, Jothirmayi R, Nair MK. Profile of pediatric malignancies: a ten year study. Ind Pediatr. 2000;37(11):1234-8.
Brown BJ, Bamgboye EA, Sodeinde O. Causes of death in childhood cancer at the Department of Paediatrics, University College Hospital, Ibadan. Afr J Med Med Sci. 2008;37(1):7-13.
Al-Asiri RH, Mott MG, Oakhill A. Causes of death in a paediatric oncology unit. Med Pediatr Oncol. 1992;20(4):315-20.