A study of brainstem evoked response audiometry in term neonates with hyperbilirubinemia
DOI:
https://doi.org/10.18203/2349-3291.ijcp20161043Keywords:
Hearing loss, BERA, ABR and hyperbilirubinemiaAbstract
Background: Brainstem evoked response audiometry (BERA) has been one of the non-invasive methods to identify the hearing abnormalities in the newborn. This study was done to determine the Incidence of hearing abnormalities during hyperbilirubinemia and to assess the Correlation of high bilirubin levels with abnormal BERA finding in the study population.
Methods: This was a longitudinal observational study comprising of 54 term babies with a mean gestational age of 38.1wks which also included 10 term low birth weight babies. Babies selected for the study had hyperbilirubinemia (>15mg/dl) due to various causes in a tertiary care hospital in Bangalore city. BERA was done in all these babies separately in the both ears using 40db and 80db stimuli at birth, 1st month and 3rd month. Consent was obtained before the start of the study. Student t-test was applied wherever necessary to analyze the data.
Results: Mean age of appearance of jaundice was 5.2 days (4-7 days). Abnormal Auditory Brain Response (ABR) changes were seen in 28 (51.9%) babies at birth, 19 infants (37%) at 1st month and 7 (13%) at 3rd month during follow up.
Conclusions: Hearing loss due to hyperbilirubinemia is a transient phenomenon, which reverts back to normal gradually, with only a small percentage going for permanent damage.
References
Sharma R, Grover N. Auditory Brain Stem Responses in Neonatal Hyperbilirubinemia and Effect of Therapy; Indian Journal of Otolaryngology and Head and Neck Surgery. 2006;58(4).
Arora SJ, Kochhar LK. Incidence Evaluation Of SNHL In High Risk Neonates; Indian Journal Of Otolarvngology And Head And Neck Surgery. 2003;55(4).
Haddad J. Hearing Loss: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, editors. Nelson Textbook of Paediatrics. 18th ed 2007:2620-26.
Downs MP. Auditory Screening. Otalarynogolic Clinics of North America. 1978;11:611-722.
Sharma P, Chhangani NP, Meena KR, Jora R, Sharma N, Gupta BD. Brainstem evoked response audiometry (BAER) in neonates with hyperbilirubinemia. Indian J Pediatr. 2006;73(5):413-6.
Muddasir M, Najar BA, Imrangattoo, Chowdhary J. Screening For Hearing Impairment In High Risk Neonates: A Hospital Based Study; Journal Of Clinical And Diagnostic Research. 2015;9(6):Sc18-21.
Perlman M, Fainmesser P, Tamari H, Yohanan W, Pevsmer B. Auditory nerve–brainstem evoked responses in hyperbilirubinemic neonates. Pediatrics. 1983;72:659-65.