A cross-sectional study of the distribution of pediatric solid tumors at an Indian tertiary cancer centre


  • Monali Madhukar Patole Department of Pediatric Surgery, NRS Medical College and Hospital, Kolkata, West Bengal, India




Cancer, Cancer epidemiology, Childhood developing countries, Pediatric solid tumours, Tumour registries, Tumour subtypes


Background: Pediatric solid tumors include a heterogeneous group of tumors, and the burden of these tumors, especially from resource-challenged countries, is not well described. The aim of this study was to describe the distribution of solid tumors in children in an Indian tertiary cancer center.

Methods: All patients under 12 years of age with histologically confirmed tumors presenting at a tertiary cancer center from January 2014 to January 2019 were identified from the hospital database. Patients with lymphomas, bone, and central nervous tumors were excluded. The demographic profile including age, sex distribution, and the treatment received were recorded for all patients.

 Results: The mean age of the eligible 153 patients was 5.7 years with majority (57.3%) in the 0-5 years age group. The male-to-female ratio was 1.6:1 with a male predominance in all tumors except germ cell tumors. Renal tumors were the most common tumors followed by neuroblastoma and soft tissue sarcoma, whereas germ cell and gonadal tumors formed only 8.49% of all tumors.

Conclusions: Extracranial and extraosseous pediatric solid tumors include a wide range of tumors with a predilection for male sex and children below 4 years of age. Wilms tumors, neuroblastoma, and soft tissue sarcomas tumors are the most common tumors.

Author Biography

Monali Madhukar Patole, Department of Pediatric Surgery, NRS Medical College and Hospital, Kolkata, West Bengal, India

Consultant department of pediatric surgery


Howard SC, Metzger ML, Wilimas JA, Quintana Y, Pui CH, Robison LL, et al. Childhood cancer epidemiology in low-income countries. Cance. 2008;112:461-72.

Kaatsch P. Epidemiology of childhood cancer. Cancer Treat Rev. 2010;36:277-85.

Rathi AK, Kumar S, Ashu A, Singh K, Bahadur A. Epidemiology of pediatric tumors at a tertiary care centre. Indian J Med Paediatr Oncol. 2007;28:33-5.

Kusuma kumary P, Jacob R, Jothirmayi R, Nair MK. Profile of pediatric malignancies: A ten year study. Indian Pediatr. 2000;37:1234-8.

Memon F, Rathi SL, Memon MH. Pattern of solid paediatric malignant neoplasm at Lumhs, Jamshoro, Pakistan. J Ayub Med Coll Abbotta. 2007;19:55-7.

Harmon BE, Friedman K, Nemesure B, Singh M. Pediatric solid malignant neoplasms: A comparative analysis. Indi J Pathol Microbiol. 2011;54:514-9.

Hesham M, Atfy M, Hassan T, Abdo M, Morsy S, El Malky M, et al. Pattern of malignant solid tumors and lymphomas in children in the east delta of Egypt: A five-year study. Oncol Lett. 2014;8:2328-32.

Adewuyi SA, Musa H, Samaila MO, Ogunrinde GO, Ameh EA, Popoola OB. Pattern of paediatric solid cancers seen in radiotherapy and oncology department, Ahmadu Bello University Teaching Hospital, Zaria-Nigeria. Niger Postgrad Med J. 2013;20:120-4.

Qureshi SS, Prabhu A, Bhagat M, Kembhavi S, Vora T, Chinnaswamy, G, et al. Outcomes of Pretreatment re-excision after unplanned excisions for Non-rhabdomyosarcoma Soft tissue sarcoma in Children. Comparison with planned excision. J Pediatr Surg. 2017;52:1340-3.

Summary-Report on Causes of Death: 2001-2003 in India. Available from: http://www.censusindia.gov.in/Vital-Statistics/Summary-Report-Death-01-03.pdf. Accessed 24 September 2013.






Original Research Articles