Impact of maternal anaemia on cord blood haemoglobin

Authors

  • Dhanasekaran Ramadoss Department of Paediatrics, Madras Medical College, Chennai, Tamil Nadu, India
  • Sumitha Arumugam Department of Pharmacology, ACS Medical college and hospital Chennai, Tamil Nadu, India
  • Suguna . Department of Paediatrics, Madras Medical College, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20192018

Keywords:

Cord blood, Hb, Maternal anaemia

Abstract

Background: Anaemia during pregnancy is associated with serious maternal and fetal complications. Cord blood hemoglobin of the newborn is an important indicator of anaemia in newborn at birth. So, this study is done to assess the impact of maternal anaemia on cord blood hemoglobin levels of neonates.

Methods: It is a cross sectional study done at government Kilpauk medical college and hospital in the department of paediatrics in year 2016.400 pregnant mothers attending the labour room in Kilpauk medical college were included and cord blood haemoglobin of their babies were collected. Mean cord blood haemoglobin of new-borns born to anaemic mothers (mild, moderate and severe) were compared with cord blood haemoglobin of new-borns born to non-anaemic mothers.

Results: Out of 400 mothers,192 mothers were anemic, and 208 mothers were non anemic. The mean maternal hemoglobin among non-anemic mothers was 16.37±0.85 and among the anemic mothers it was 15.03±1.04. The mean cord hemoglobin of neonates born to anemic mothers among the three groups (mild moderate severe) were compared with mean cord hemoglobin of the non-anemic group. The difference between groups were statistically significant with P values <0.05,0.01 and 0.05 respectively.

Conclusions: In present study maternal anaemia affects the cord blood haemoglobin of neonates. Present study infers that anaemic mothers deliver babies with lower haemoglobin compared to non-anaemic mothers. Authors have found a linear relationship between maternal haemoglobin and cord blood haemoglobin of the new-borns.

References

WHO. Iron deficiency anaemia assessment prevention and control. A guide for programme managers. Geneva, Switzerland: WHO. 2001.Accessed at: https://www.who.int/nutrition/publications/micronutrients/anaemia_iron_deficiency/WHO_NHD_01.3/en/.

McLean E, Cogswell M, Egli I, Wojdyla D, De Benoist B. Worldwide prevalence of anaemia, WHO vitamin and mineral nutrition information system, 1993-2005. Public Health Nutrit. 2009;12(4):444-54.

Jaleel R, Khan A. Severe anaemia and adverse pregnancy outcome. J Surg Pak.2008;13(4):147.

Cohen JH, Haas JD. Hemoglobin correction factors for estimating the prevalence of iron deficiency anemia in pregnant women residing at high altitudes in Bolivia. Pan Am J Public Health. 1999;6:392-9.

Pregnancy complications. Centre for diseases control and prevention. Accessed at: http:// https://www.cdc.gov/reproductivehealth/maternalinfanthealth/pregnancy-complications.html.Accessed on : Jun 6 2016.

Perutz MF. Stereochemistry of cooperative effects in haemoglobin: haem-haem interaction and the problem of allostery. Nature. 1970;228(5273):726.

Fenton V, Cavill I, Fisher J. Iron stores in pregnancy. Brit J Haematol. 1977;37(1):145-9.

Sisson TRC, Lund CJ. The influence of maternal iron deficiency on the new born. Am J Dis child. 1957;94:525.

Nhonoli AM, Kihama FE, Ramji BD. The relation between maternal and cord serum iron levels and its effect on fetal growth in iron deficlent mothers without malarial infection. BJOG: Int J Obstetr Gynaecol. 1975;82(6):467-0.

Najeeba CM, Prabhu AS. Maternal anaemia and its effect on cord blood haemoglobin and new-born birthweight. IOSR. 2015;14(7):30-2.

Debbarma R, Debbarma B, Devi MA. Effect of maternal anaemia on cord haemoglobin and birth weight of newborn. IOSR. 2015;14(7):19-21.

Mamoury GH, Hamedy AB, Akhlaghi F. Cord hemoglobin in newborns in correlation with maternal hemoglobin in northeastern Iran. Iran J Med Sci. 2015;28(4):166-8.

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Published

2019-04-30

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Original Research Articles