Clinical and imaging correlation of cerebral palsy: a retrospective study in a tertiary care centre


  • Swathi S. Sanjee Department of Pediatrics, AJ Institute of Medical Sciences, Kuntikana, Mangalore, Karnataka, India
  • Chandrashekhara G. Shettigar Department of Pediatrics, AJ Institute of Medical Sciences, Kuntikana, Mangalore, Karnataka, India
  • Santosh T. Soans Department of Pediatrics, AJ Institute of Medical Sciences, Kuntikana, Mangalore, Karnataka, India



Cerebral palsy, Magnetic resonance imaging


Background: Cerebral Palsy is the most common chronic motor disorder of childhood. Clinical spectrum is different in developing and developed countries. Aim of the study was to evaluate the clinical profile, co-morbidities and the imaging correlate of children with CP.

Methods: Data was collected retrospectively from individual case records from March 2016 to October 2018. All children aged 2 years and above with clinical signs of cerebral palsy were included in the study.

Results: A total of 78 children had the diagnosis of cerebral palsy, out of which 63 cases were included which satisfied the inclusion criteria. Most of the children were born out of singleton pregnancy (90.4%). The mean gestational age was 36.94±1.48 weeks. Most common type of cerebral palsy noted in present study was spastic quadriplegic type (n=34) followed by diplegic type (n=14). Epilepsy was associated in 36.5% (n=23) of children, and most commonly associated with spastic quadriplegic type of cerebral palsy(n=16). Other associated abnormalities included mental retardation, speech, hearing, cognitive, and behavioral abnormalities. Magnetic resonance imaging was normal in 60.3% (n=38) of children and abnormal in 39.68% (n=25) of children. Diffuse cerebral atrophy was the most common abnormal finding (n=9). Other abnormal findings included periventricular leucomalacia, basal ganglia lesions, cortical/subcortical lesion, focal infarcts and miscellaneous lesions.

Conclusions: MRI helps in knowing the pathological basis of the disease, but clinical findings carry utmost importance. MRI positivity was seen in only 39.68% of cases. Hearing abnormalities being the most common association, proper screening tests and regular follow up is very essential.


Gladstone M. A review of the incidence and prevalence, types and etiology of childhood cerebral palsy in resource-poor settings. Ann Trop Paediatr. 2010;30:181-96.

Bax M, Goldstein M, Rosenbaum P, Leviton A, Paneth N, Dan B, et al. Proposed definition and classification of cerebral palsy. Dev Med Child Neurol. 2005;47:571-6.

Singhi PD, Ray M, Suri G. Clinical spectrum of cerebral palsy in North India-an analysis of 1,000 cases. J Trop Pediatr. 2002;48:162-6.

Riikonen R, Raumavrita S, Sinivuori E, Seppala T. Changing pattern of cerebral palsy in the southwest region of Finland. Acta Paediatr Scand. 1989;78:581-87.

Nelson KB, Ellengberg JH. Aantecedents of cerebral palsy. Multi-variate analysis of risks. New Engl J Med. 1986;315:81-6.

Dale A, Stanley FJ. An epidemiological study of cerebral palsy in western Australia, 1956-1975. II: Spastic cerebral palsy and perinatal factors. Dev Med Child Neurol. 1980;22:13-25.

Nelson KB, Grether JK, Velie EM. Cerebral palsy in four northern California countries, births 1983 through 1985. J Paediatr. 1993;123:230-37.

O’Reilly DE, Walentynawicz JE. Etiological factors in cerebral palsy. A historical review. Dev Med Child Neurol. 1981;23:633-42.

Powell TG, Pharoah POD, Cooke RW, Rosenblom L. Cerebral palsy in low birth weight infants, I spastic hemiplegia: association with intrapartum stress. Dev Med Child Neurol. 1988;30:11-18.

Aicardi J. Epilepsy and cerebral palsy. In: Aicardi J (ed.), Epilepsy in Children, 2nd ed. Raven Press, New York; 1994:350-51.

Rempel GR, Colwell SO, Nelson RP. Growth in children with cerebral palsy fed via gastrostomy. Paediatr. 1988;82:857-62.

Jones PM. Feeding disorders in children with multiple handicaps. Dev Med Child Neurol. 1989;31:404-6.

Bax M, Tydeman C, Flodmark O. Clinical and MRI correlates of cerebral palsy: the European cerebral palsy study. JAMA. 2006 Oct 4;296(13):1602-8.






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