Outcome of pre-term babies born in tertiary care institute
DOI:
https://doi.org/10.18203/2349-3291.ijcp20190721Keywords:
Preterm, Respiratory distress syndrome (RDS), SepsisAbstract
Background: Preterm babies’ survival has improved with advances in neonatology care in this era. Even with advances in treatments, there is still morbidity and mortality among preterm. The objective of this study was to know the incidence of prematurity and complications seen in them.
Methods: A cross sectional study was conducted on all preterm babies born in Sapthagiri Institute of Medical Sciences, Bangalore, over period of one year from 1st August 2017 to July 2018.
Results: Out of 500 babies born, 110 babies had RDS, among 110 babies 85 cases were preterm RDS babies included in study. Majority were males 55 (64.5%) and females 30 (35.2%). The gestational age group was maximum in the 28-32weeks,the most common morbidity noted was sepsis (77.7%) and RDS (22%). Death was 9(10.5%) only 4(4.7%) needed intervention in the form of CPAP.
Conclusions: The study concluded that males were commonly affected by respiratory distress syndrome, sepsis was a common cause for morbidity and mortality. Inspite of advances in neonatology sepsis continues to be a leading cause of death. Proper hand cleansing has to be emphasized and reinforced to prevent sepsis in NICU. The best possible attempts to delay preterm delivery have to be followed. One should have a high index of suspicion and low threshold to treat sepsis in preterm.
References
Infant respiratory distress syndrome. [cited 2016 March 22] Available at: https://en.wikipedia.org/wiki/Infant_respiratory_distress_syndrome.
Hyaline membrane disease [cited 2016 March 22] Available at: https://www.medicinenet.com/script/main/art.asp?articlekey=10677.
Rodriguez RJ. Respiratory distress syndrome and its management. Neonatal-Perinatal Med. 2002:1001-117.
Usher R the respiratory distress syndrome of prematurity ped.clin North America. 1961;8;525.
Sharma M. Preterm infants: is prophylactic surfactant therapy and early vitamin A supplementation the way ahead?. Med J Armed Forces India. 2011;67(2):102-3.
Edwards MO, Kotecha SJ, Kotecha S. Respiratory distress of the term newborn infant. Paediatr Respir Rev. 2013;14(1):29-36.
Warren JB, Anderson JM. Newborn respiratory disorders. Pediatr Rev. 2010;31(12):487-95.
A S, PN R S, Jose J. Downes Score vs. Silverman Anderson Score for Assessment of Respiratory Distress in Preterm Newborns. Pediatric Oncall. 2016[cited 2016 July-September 1];13. Art #30. Available at: http://www.pediatriconcall.com/pediatric journal/View/fulltext-articles/1027/J/0/0/542/0.
Crowley P. Antenatal corticosteroid therapy: a meta-analysis of the randomized controlled trials, 1972 to 1994. Am J Obstet Gynecol. 1995;173:322-35.
Given J. Respiratory distress syndrome. In Berman's Pediatric Decision Making (Fifth Edition). 2011. [cited 2016 March 22] Available at: http://www.sciencedirect.com/topics/medicine-and-dentistry/infant-respiratory-distress-syndrome.
Col KN, Col CW, Col BR, Col SS. Incidence and etiology of respiratory distress in newborn. Med J Armed Forces India. 1999;55(4):331-3.
Townsel CD, Emmer SF, Campbell WA, Hussain N. Gender differences in respiratory morbidity and mortality of preterm neonates. Frontiers Pediatr. 2017;5:6.
Fleisher B, Kulovich MV, Hallman M, Gluck L. Lung profile: sex differences in normal pregnancy. Obstet Gynecol. 1985; 66(3):327-30.
Saboute M, Kashaki M, Bordbar A, Khalessi N, Farahani Z. The Incidence of respiratory distress syndrome among preterm infants admitted to neonatal intensive care unit: A retrospective study. Open J Pediatr. 2015;5:285-9.
Hamilton BE, Martin JA, Osterman MJK, Curtin SC, Mathews TJ. Births: Final data for 2014. Natl Vital Stat Rep. 2015;64(12):8.
Reuter S, Moser C, Baack M. Respiratory distress in the new-born. Pediatr Review. 2014;35(10):417.
Shrestha S, Karki U. Indications of admission and outcome in a newly established neonatal intensive care unit in a developing country (Nepal). Nepal Med College J. 2012;14(1):64-7.
Ersch J, Roth-Kleiner M, Baeckert P, Bucher HU. Increasing incidence of respiratory distress in neonates. Acta Paediatr.2007;96(11):1577-81.
Mathai S, Raju U, Kanitkar M. Management of Respiratory Distress in the Newborn. Med J, Armed Forces India.2007;63(3):269-72.
The World health organisation young infant study group. Bacterial etiology of serious bacterial infections in young infants in developing countries: Results of a multicenter study. Pediatr Infect Dis J. 1999;18(10):S17-22.
Sunil B, Girish N, Bhuyan M. Outcome of preterm babies with respiratory distress syndrome on nasal CPAP. Int J Contemporary Pediatr.2017; 4(4):1206-9.
Neonatal morbidity and mortality: Report of the national neonatal perinatal data base. Indian Pediatr. 1997;34:1039-42.
Bersani I, Thomas W, Speer CP. Chorioamnionitis- the good or the evil for neonatal outcome? J Matern Fetal Neonatal Med. 2012;25(1):12-6.
Been JV, Zimmermann LJ. Histological chorioamnionitis and respiratory outcome in preterm infants. Arch Dis Child Fetal Neonatal Ed. 2009;94(3):F218-25.
