Health profile of paediatric tuberculosis patients on directly observed treatment short course therapy


  • Sachin T. Bandichhode Department of Pediatrics, Dr. Vaishampayan Memorial Government Medical College, Solapur, Maharashtra
  • Viresh A. Nandimath Department of Community Medicine, Dr. Vaishampayan Memorial Government Medical College, Solapur, Maharashtra



DOTS, Default, Outcome, PEM, Relapse, TB, Treatment failure


Background:Children are especially vulnerable to tuberculosis due to close contact with family members and it is often difficult to diagnose and treat it in young children. The objective of this study was to study clinical profile of paediatric TB patients. To assess outcome of directly observed treatment short course (DOTS) among paediatric TB patients.

Methods: A descriptive longitudinal study conducted in all paediatric (1-15 years) patients registered for tuberculosis treatment in city tuberculosis center Solapur during 1st November 2010 to 31st December 2012. A pre-designed, pre-tested structural questionnaire was used for data collection. Physical examination was undertaken after the interview was over.

Results:93 paediatric TB patients were registered for DOTS. Male to female patient’s ratio was almost equal. Most of the TB patients (35.56%) were in 01 to 05 years of age group. Most of the patients (91) presented with cough for more than two weeks; with other symptoms like evening rise of fever, dyspnea, loss of appetite, swelling over neck. Out of 93 patients 70 patients had protein energy malnutrition (PEM). 84.95% patients were completed the DOTS treatment, while 3.22% were defaulter and outcome in 1.05% was treatment failure.

Conclusions:DOTS completion rate among paediatric TB patients is considerably high, protein energy malnutrition have the association with paediatric tuberculosis.


The burden of disease caused by TB- global tuberculosis WHO report 2014. Available at Accessed on 10 June 2016.

Swaminathan S, Banu R. Pediatric tuberculosis: global overview and challenges. Clin Infect Dise. 2010;50(S3):S184-194.

Marais BJ. Tuberculosis in children. Pediatr Pulmonol. 2008;43(4):322-9.

Bai S, Devi L. Clinical spectrum of tuberculosis in BCG vaccinated children. Indian Pediatr. 2001;39:458-62.

Ramesh, Shoba A, Manjula VD. Treatment outcomes of childhood tuberculosis with DOTS strategy in Kottayam, Kerala. Indian J Com Health. 2012;24(4):280-4.

Goyal A, Shah I, Patankar N, Chilkar S. Clinical profile of children with pulmonary Tuberculosis. Clin Epide Global Health. 2014;2(1):24-7.

Sreeramareddy CT, Ramakrishnareddy N, Shah RK, Baniya R, Swain PK. Clinico-epidemiological profile and diagnostic procedures of pediatric tuberculosis in a tertiary care hospital of western Nepal-a case-series analysis. BMC Pediatrics. 2010;57:1-7.

Shrestha S, Bichha RP, Sharma A, Upadhyay S, Rijal P. Clinical profile of tuberculosis in children. Nepal Med Coll J. 2011;13(2):119-22.

Vijayasekaran D, Kumar RA, Gowrishankar NC, Nedunchelian K, Sethuraman S. Mantoux and contact positivity in tuberculosis. Indian J Pediatr. 2006;73(11):989-93.

Seth V, Kabra SK, Lodha R. Management of tuberculosis. In Essentials of Tuberculosis in Children 2nd Edition, Eds Seth V, Kabra SK. Delhi Jaypee Brothers; 2001:349-354.

Thakor N, Prajapati D. Health and socio-demographic profile of paediatric tuberculosis patients on DOTS therapy in Ahmadabad city. Int J Med Sci Public Health. 2014;3:1123-6.

Baily GV. Tuberculosis prevention trial, Madras. Indian J Med Res. 1980;72(Suppl):1-74.

Karonga. Prevention trial group. Randomised controlled trial of single BCG, repeated BCG, or combined BCG and killed mycobacterium leprae vaccine for prevention of leprosy and tuberculosis in Malawi. Lancet. 1996;348:17-24.

Hart PD, Sutherland I. BCG and vole bacillus vaccines in the prevention of tuberculosis in adolescence and early adult life. Br Med J. 1977;2:293-5.

Gocmen A, Ozgelic U, Kiper N, Toppare M, Kaya S, Cengizlier R, et al. Short course intermittent chemotherapy in childhood tuberculosis. Infection. 1993;21:324-7.

Arora VK, Gupta R. Directly observed treatment for tuberculosis. Indian J Pediatr. 2003;70(11):885-9.

Sharma S, Sarin R, Khalid UK, Singla N, Sharma PP, Behera D. Clinical profile and treatment outcome of tuberculous lymphadenitis in children using dots strategy. Indian J Tuberc. 2010;57:4-11.

Satyanarayana S, Shivashankar R, Vashist RP, Chauhan LS, Chadha SS, Dewan PK, et al. Characteristics and programme-defined treatment outcomes among childhood tuberculosis (TB) patients under the National TB programme in Delhi; 2010.

Indumathi CK, Prasanna KK, Dinakar C, Shet A, Lewin S. Intermittent short course therapy for pediatric tuberculosis. Indian Paediatr. 2010;47:93-






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