A study of neonatal morbidity in preterm premature rupture of membrane mother


  • Manjul Vijay Department of Paediatrics, Katihar Medical College, Katihar, Bihar
  • Tejaswi Nandan Department of Obstetrics and Gynaecology, Katihar Medical College, Katihar, Bihar
  • Binay Ranjan Department of Paediatrics, Katihar Medical College, Katihar, Bihar




Neonatal morbidity, PROM, RDS, Sepsis


Background: Premature rupture of membrane is one of the most common problems in obstetrics with 5-10% of term pregnancies. The aim was to study morbidity in neonates born to mothers with preterm premature rupture of membrane (PROM) more than 18 hours.

Methods: This is a prospective study in which a total of 50 neonates admitted in NICU in Katihar medical college and hospital, Bihar, India, born to mothers of PROM more than 18 hours were included in this study. Clearance from ethical committee was taken. Neonates born to mothers with antepartum haemorrhage, meconium aspiration syndrome, toxemia of pregnancy and rh-incompatibility were excluded from the study. Proper history, examination and laboratory tests were done and data were analysed using SSP-20.

Results:Among the included neonates, the most common clinical manifestations were respiratory distress syndrome 18 cases (36%), septicemia 4 cases (8%), meningitis 1 case (2%) and pneumonia 1 case (2%).

Conclusions:Neonates born to mothers with PROM are at high risk and active management is needed to deliver the baby within 24 hours of PROM for better neonatal outcome.  


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Original Research Articles