DOI: http://dx.doi.org/10.18203/2349-3291.ijcp20181503

Study of prevalence and clinical spectrum of seizures in children in a teaching hospital in rural Telangana, India

C. P. V. Ramana Sastry, R. Manohar Reddy

Abstract


Background: To study the prevalence and clinical spectrum of seizures and treatment outcome in children.

Methods: A hospital based prospective study was done at Maheshwara Medical College and Hospital, Patancheru, Telangana in the department of Paediatrics over one-year period. A total of 75 cases presenting with seizures were studied for demographics, clinical features, imaging studies where possible and patient response to treatment.  

Results: T Patient age ranged from one week to 14 years with male to female ratio of 1:4. Majority were in the age group of 1-3 years 25/75 (33.3%). Fever was present on admission in 66.6% of cases in 1 month to 6 years. Unprovoked seizure was common 20/75 (26.6%) in age group 6 to14 years. Neonatal seizures were seen in 6.6% cases. Generalized tonic clonic seizures were common and were seen in 63.3% cases. Only 5 (6.6 %) cases presented with status epilepticus. CT scan was done in 20 cases in unprovoked seizures and showed various etiologies.

Conclusions: Seizures in children are a common indication for hospital admission. They can be febrile or unprovoked. CNS infections and space occupying lesions are common causes for paediatric seizures. Early detection of the cause of seizures helps in instituting appropriate treatment. Children with unprovoked seizures should be on regular long term follow up and treatment.


Keywords


Afebrile seizures, Neurocysticercosis, Seizures in children, Unprovoked seizures

Full Text:

PDF

References


Ottman R. Progress in the genetics of the partial epilepsies. Epilepsia. 2001;42(5):24-30

Kramer U. Epilepsy in the first year of life: A review. J child Neurol. 1999;14(8):485-9

Shawki A. Etiological and clinical presentation of epilepsy in upper Egypt M.D Thesis in Neurology .Faculty of Medicine, Assiut University 1995

Beilmann A, Napa A, Sööt A, Talvik I, Talvik T. Prevalence of childhood epilepsy in Estonia. Epilepsia. 1999;40(7):1011-19.

Serdaroglu A, Ozkan S, Aydin K, et al. Prevalence of epilepsy in Turkish children between the ages of 0 and16 years. J Child Neurol. 2004;19(4):271.

Radhakrishnan K, Pandian JD, Santhoshkumar T, Thomas SV, Deetha TD, Sarma PS et al., Prevalence, knowledge, attitude, and practice of epilepsy in Kerala, South India. Epilepsia 2000;41(8):1027-35.

International League Against Epilepsy. Commission on Tropical Diseases of the International League against Epilepsy: relationship between epilepsy and tropical diseases. Epilepsia. 1994;35:89-93.

Hauser WA: The prevalence and incidence of convulsive disorders in children. Epilepsia 1994; 35(2):S1-6.

Martindale JL, Goldstein JN, Pallin DJ: Emergency department seizure epidemiology. Emerg Med Clin North Am 2011;29(1):15–27.

Idro R, Gwer S, Kahindi M, Gatakaa H, Kazungu T, Ndiritu M, et al., The incidence, aetiology and outcome of acute seizures in children admitted to a rural Kenyan district hospital. BMC Pediatr. 2008, 8(1):5.

Commission on Epidemiology and Prognosis: International League Against Epilepsy. Guideline for epidemiologic studies on epilepsy. Epilepsia 1993;34(4):592-6.

Prober CG, Dyner LL: Central nervous system infections. In Nelson Textbook of Pediatrics. 19th ed. Philadelphia PA: W.B. Saunders; 2012:2088.

Scott RC. What are the effects of prolonged seizures in the brain? Epileptic Disord 2014;1:S6-11.

Saravanan S. Profile of children admitted with seizures in a tertiary care hospital in South India. IOSR J Dent Med Sci 2013;11(4):56-61.

Chaudhary N, Gupta MM, Shrestha S, Pathak S, Kurmi OP, Bhatia BD, et al. Clinicodemographic Profile of Children with Seizures in a Tertiary Care Hospital: A Cross-Sectional Observational Study. Neurology research international. 2017;2017.

Mwipopo EE, Akhatar S, Fan P, Zhao D. Profile and clinical characterization of seizures in hospitalized children. Pan Afr Med Jr 2016;16(24):313.

Kandil MR, Ahmed WM, Sayed AM, Hamed SA. Pattern of epilepsy in childhood and adolescence: a hospital-based study. African Journal of Neuro Sci 2007;26(1):33-44.

Dhakal AK, Shakya H, Shakya A, Shah SC, Mehata S. Clinical characteristics of children with febrile seizure. J Nepal Health Res Counc 2014;12(28):162-6.