Association of azotemia with hypoglycemia in severe acute malnutrition how much concerning?

Syed Manazir Ali, Hari Shankar Meshram


Background: Hypoglycemia is a known complication of SAM which is to be managed early to prevent morbidity and mortality. There is lack of literature regarding hypoglycemia and its associated factors in SAM children. This study aimed to evaluate predicting factors associated with hypoglycemia in children with severe acute malnutrition (SAM) in NRC.

Methods: In this case-control design, we compared clinical and laboratory characteristics of children with and without hypoglycemia taken from a population of 299 children with SAM admitted in NRC.

Results: Prevalence of hypoglycemia in SAM was 14%. Amongst the association it was found that deranged creatinine (P value of 0.002, odds ratio 2.9, 95% C.I.1.48 - 5.97) and deranged urea (P value 0.0001, odds ratio 3.6, 95% C.I. 1.79 - 7.2) were statistically significant. Diarrhoea (P value 0.7, odds ratio 1.14, 95% C.I. 0.57 - 2.26), leucocytosis (P value 0.23, odds ratio 0.54, 95% C.I. 0.21 - 2.26), leucopenia ( P value 0.6, odds ratio 0.42, 95% C.I. 0.05 - 3.35) were found statistically insignificant.

Conclusions: Azotemia in SAM was found significantly associated with hyponatremia. 


Azotemia, Hypoglycemia, Severe acute malnutrition

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