DOI: http://dx.doi.org/10.18203/2349-3291.ijcp20164613

Association of azotemia with hypoglycemia in severe acute malnutrition how much concerning?

Syed Manazir Ali, Hari Shankar Meshram

Abstract


Background: Hypoglycemia is a known complication of SAM which is to be managed early to prevent morbidity and mortality. There is lack of literature regarding hypoglycemia and its associated factors in SAM children. This study aimed to evaluate predicting factors associated with hypoglycemia in children with severe acute malnutrition (SAM) in NRC.

Methods: In this case-control design, we compared clinical and laboratory characteristics of children with and without hypoglycemia taken from a population of 299 children with SAM admitted in NRC.

Results: Prevalence of hypoglycemia in SAM was 14%. Amongst the association it was found that deranged creatinine (P value of 0.002, odds ratio 2.9, 95% C.I.1.48 - 5.97) and deranged urea (P value 0.0001, odds ratio 3.6, 95% C.I. 1.79 - 7.2) were statistically significant. Diarrhoea (P value 0.7, odds ratio 1.14, 95% C.I. 0.57 - 2.26), leucocytosis (P value 0.23, odds ratio 0.54, 95% C.I. 0.21 - 2.26), leucopenia ( P value 0.6, odds ratio 0.42, 95% C.I. 0.05 - 3.35) were found statistically insignificant.

Conclusions: Azotemia in SAM was found significantly associated with hyponatremia. 


Keywords


Azotemia, Hypoglycemia, Severe acute malnutrition

Full Text:

PDF

References


Black RE, Allen LH, Bhutta ZA, Caulfield LE, Onis M, Ezzati M, et al. Maternal and child undernutrition: globaland regional exposures and health consequences. Lancet. 2008;371:243-60.

Heikens GT. How can we improve the care of severely malnourished children in Africa? PLoS Med. 2007;4:45.

Heikens GT, Bunn J, Amadi B, Manary M, Chhagan M,Berkley JA, et al. Case management of HIV-infected severely malnourished children: challenges in the area of highest prevalence. Lancet. 2008;371:1305-7.

Gangaraj S, Das G, Madhulata S. Electrolytes and blood sugar changes in severely acute malnourished children and its association with diarrhoea and vomiting. Int J Pharmaceutical Sci. 2013;33-36.

Seth A, Aneja S. Hyperglycemia in malnourished children with dehydrating gastroenteritis. Indian J Pediatr. 1995;62:353-5.

Fronius KE, Kaiser E. Hypoglycaemia in infantile malnutrition. Acta Paediatr Scand. 1967;172:119.