DOI: http://dx.doi.org/10.18203/2349-3291.ijcp20175571

Prevalence of congenital anomalies: a hospital-based study

Prathiba N. Doddabasappa, Adarsh E., Divya N.

Abstract


Background: Birth defects are a diverse group of disorders with prenatal origin that can be caused by single gene defects, chromosomal disorders, multifactorial inheritance, environmental teratogens and or micronutrient deficiencies. The objective of this study was to study the prevalence of congenital anomalies in Department of Pediatrics at Rajarajeswari Medical College and Hospital, Kambipura, Bangalore.

Methods: The study population includes all babies born between 1 August 2015 and 31st July 2016. The babies were examined and assessed thoroughly for the presence of a congenital anomaly and were then distributed system wise by the pediatrician. Surgical conditions were also reevaluated by a pediatric surgeon.

Results: Among the 2,137 deliveries, 86 babies had congenital malformations. Prematurity, consanguinity and increased maternal age elevate the appearance of congenital anomalies. The cardiovascular malformations were most common with a prevalence rate of 4%.

Conclusions: Congenital anomalies are a global health problem. Thus, this study supports us to understand the prevalence of congenital anomalies. There is no association of congenital malformations with low birth weight babies. Consanguinity should be discouraged. Early antenatal scan aids in prior detection of congenital anomalies Appropriate genetic counselling can reduce the anomalies in future pregnancies.


Keywords


Congenital malformations, Prevalence

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References


Dastgiri S, Shiekhzadeh Y, Dastgiri A. Monitoring of congenital anomalies in developing countries: a pilot model in Iran. Studies in Health Technology and Informatics. 2011;164:157-61.

Carmona RH. The global challenges of birth defects and disabilities. Lancet. 2005;366(9492):1142-4.

World Health Organization. Birth defects. Executive Board, 126th session, provisional agenda, December 2009; EB 126/10. Available at http://apps.who.int/gb/ebwha/pdf_files/EB126/B126_10-en.pdf

Tanteles GA, Suri M. Classification and etiology of birth defects. Pedi Pediatr Child Health 2007;17:233-43.

Agarwal SS, Singh U, Singh PS, Singh SS, Das V, Sharma A, et al. Prevalence and spectrum of congenital malformations in a prospective study at a teaching hospital. Indian J Med Res. 1991;94:413-9.

Chaturvedi P, Banerjee KS. Spectrum of congenital malformations in newborns from rural Maharashtra. Indian J Pediatr. 1989;56(4):501-7.

Datta V, Chaturvedi P. Congenital malformations in rural Maharashtra. Indian Pediatr. 2000;37:998-1001.

Swain S, Agrawal A, Bhatia BD. Congenital malformations at birth. India Pediatr. 1994;31:1187-91.

Gupta RK. Pattern of congenital anomalies in newborn: a hospital based prospective study. JK Sci. 2009;2:34-6.

Jehangir W, Ali F, Jahangir T, Masood MS. Prevalence of gross congenital malformations at birth in the neonates in a tertiary care hospital. InAPMC. 2009;3(1):47-50.

Al Shehri MA. Pattern of major congenitalanomalies in South Western Saudi Arabia. Bahrain Med Bull. 2005;27:302-7.

Ahmadzadeh A, Safikhani Z, Abdulahi M. Congenital malformations among live births at Atvand Hospital, Ahwaz. Iran Pak Med J. 2008;24:33-7.

Gupta RK, Gupta CR, Singh D. Incidence of congenital malformations of musculoskeletal system in new live borns in Jammu. JK Sci. 2003;5:157-60.

Jones KL. Smith's recognizable patterns of human malformation. 7th edition. Philadelphia: WB Saunders; 2013:1.

Sugunabi NS, Mascarane M, Syamala K, Nair PM. An etiological study of congenital malformations in newborn. Indian Pediatr. 1982;19:1003-7.

Indian Council of Medical Research, New Delhi. Reproductive health. Annual report 2002-03:91. Available at http://icmr.nic.in/annual/hqds2003/English/Reproductive%20Health.pdf