Scabies in children and its outcome with topical permethrin and oral ivermectin: a single center prospective study


  • Balasaheb B. Suroshe Department of Pediatrics, Government Medical College and Cancer Hospital, Aurangabad, Maharashtra, India
  • Kishor G. Rathod Department of Pediatrics, Dr. Shankarrao Chavan Government Medical College, Nanded, Maharashtra, India
  • Vasant S. Kulkarni Department of Pediatrics, Seth GS Medical College, Mumbai, Maharashtra, India
  • Rakesh R. Chikhlonde Department of Pediatrics, Government Medical College, Aurangabad, Maharashtra, India



Children, Ivermectin, Permethrin, Scabies


Background: Scabies is highly prevalent in children less than 6 years and more so in less than 2 years of age. Treating scabies in infants and children is challenging. The objective was to study the characteristics and distribution of lesions and outcome with topical Permethrin and Oral Ivermectin in scabies in children.

Methods: 264 cases of scabies from the skin and pediatric outpatient of a tertiary care center were enrolled.

Results: It is common in children below 5 years of age. The effectiveness of local Permethrin and oral Ivermectin was not significantly different in the form of complete cure.

Conclusions: Children tend to scratch the rash repeatedly, the scratch marks and crusting of the rash sometimes make this infection hard to identify, hence high index of suspicion is required to diagnose. Complicated lesions in scabies require more duration than uncomplicated lesions. Permethrin and Ivermectin are equally effective in scabies. Ivermectin being orally administered is a drug of choice in epidemics. 


Nair BKH, Joseph A, Narayanan PI. Epidemiology of scabies. Indian J Dermatol Venereol. 1973;39:101-5.

Heilesen B. Studies on Acarus scabiei and scabies. Acta Derm Venereol (Stockh). 1946;14:1-370.

Sarkar R, Amrinder J. Kanwar, Three common Dermatological disorders in children (Scabies, Pediculosis and Dermatophytoses), Indian Pediatr. 2001;38:995-1008.

Thappa DM. Common skin problems. Indian J Pediatr. 2002;69:701-6.

Pramanik AK, Hansen RC. Transcutaneous Gamma benzene hexachloride absorption and toxicity in infants and children. Arch Demerol. 1979;115:1224-5.

Schachner B. Treatment of scabies and pediculosis with lindane preparations: An evaluation. J Am Acad Dermatol. 1981;5:517-27.

Jaramillo F, Ayerbe. Ivermectin for Crusted Norwegian Scabies. Arch Dermatol. 1998;134:143-5.

Strong M, Johnstone PW. Interventions for treating scabies. Cochrane Database Syst Rev. 2007;3.

Dressler C, Rosumeck S, Sunderkötter C, Werner RN, Nast A. The Treatment of Scabies. Dtsch Arztebl Int. 2016;113(45):757-62.

Crissey JT. Scabies and Pediculosis Pubis, Urologic Clin North Am. 1984;11(1):171-6.

Wakhlu I, Thakur S. Clinical profile of scabies in North Indian children. Indian Pediatr. 1988;(25):1050-3.

Davis DE. Lindane Poisoning. Arch Dermatol. 1983;119:142.

Taplin D. Scabies in Children. Pediatric Dermatol. 1990;7:67-73.

Terri L, Meinking BA. Scabies therapy for the millennium. Pediatr Dermatol. 2000;17:154-6.

Gopalkrishnan UV, Nair TV. Comparative study of oral ivermectin and topical permethrin cream in the treatment of scabies, in Infestations. Yearbook Dermatol Dermatologic Surg. 2001:175-8.

Heukelbach J. Ectoparasites: the under estimated Realm. Lancet. 2004;13:889-91.






Original Research Articles