Infantile tremor syndrome

Apoorva Sree Puttagunta; Shruthi T. K.; Shubha S.; Rajakumar P. S.

doi:10.18203/2349-3291.ijcp20174763

Authors

Apoorva Sree Puttagunta Department of Pediatrics, Sri Ramachandra Medical College, Chennai, Tamil Nadu, India
Shruthi T. K. Department of Pediatrics, Sri Ramachandra Medical College, Chennai, Tamil Nadu, India
Shubha S. Department of Pediatrics, Sri Ramachandra Medical College, Chennai, Tamil Nadu, India
Rajakumar P. S. Department of Pediatrics, Sri Ramachandra Medical College, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20174763

Keywords:

Acrodermatitis, Infantile tremor syndrome, Vitamin B12 deficiency

Abstract

Infantile tremor syndrome (ITS) is defined by the tetrad of pallor, developmental delay/regression, skin pigmentation, and brown scanty scalp hair. Involuntary movements in the form of tremors supervene in the natural course of the illness in a significant number of cases. The disorder is common in exclusively breast-fed infants of vegetarian mothers. Most of the children eventually recover but are frequently left with long-term cognitive and language neurodeficits. This review attempts to provide comprehensive and up-to-date information on the subject incorporating recently published studies.

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