Monophasic synovial sarcoma: a case report and literature review

Authors

  • Ahana Gupta Department of Paediatrics, Shri Guru Ram Rai Institute of Medical & Health Science, Dehradun, Uttarakhand
  • Monika Choudhary Department of Pathology, Sardar Patel Medical College, Bikaner, Rajasthan
  • Neelu Gupta Department of Pathology, Sardar Patel Medical College, Bikaner, Rajasthan
  • Sunita Kulhari Department of Pathology, Sardar Patel Medical College, Bikaner, Rajasthan
  • Sandeep Pachar Department of Respiratory Medicine, Sardar Patel Medical College, Bikaner, Rajasthan

DOI:

https://doi.org/10.18203/2349-3291.ijcp20162397

Keywords:

Monophasic, Synovial sarcoma, Paediatric tumor

Abstract

Synovial sarcoma is an aggressive soft tissue tumor which accounts for 7% - 8% of all human malignant sarcomas. Although this tumor generally affects adults, about 30% of reported cases occur in children and adolescents. Synovial sarcoma is the most common malignant non-rhabdomyosarcomatous soft tissue sarcoma in children and adolescents. We report a case of synovial sarcoma presented with pain and swelling in the left knee. MRI of left knee shows 25×54×56 mm soft tissue lesion in infrapatellar bursa. FNAC left knee swelling reported malignant spindle cell tumor. The mass was completely resected in a surgical procedure. In pathological examination of the mass, monomorphic fibroblastic synovial sarcoma was reported. Patient was treated with Ifosfamide and Adriamycin.

References

Enzinger FM, Weiss SW. Soft tissue tumors. 2nd ed. St. Louis: Mosby Company, 1988.

Baptista AM, Camarago OP, Croci AT, Oliveira CR. Synovial sarcoma of the extremities: prognostic factors for 20 nonmetastatic cases and a new histologic grading system with prognostic significance. Clinics, Sao Paulo. 2006;61(5):381-6.

Perez CA. Unusual nonepithelial tumors of head and neck. Principles and practice of radiation oncology. 1998;43:1125-34.

Weiss SW, Goldblum JR. Malignant Soft Tissue Tumors of Uncertain Type. In Weiss SW, Goldblum JR: Soft Tissue Tumors, 4th ed., St. Louis, Mosby, 2001.

Miettinen M, Virtanen I. Synovial sarcoma - a misnomer. Am J Pathol. 1984;117:18-25.

Bos GD, Esther RJ. Foot tumors: diagnosis and treatment. J Amer Acad Orthop Surg. 2002;10:259-70.

Machen SK, Easley KA, Goldblum JR. Synovial sarcoma of the extremities: a clinicopathologic study of 34 cases, including semi-quantitative analysis of spindled, epithelial, and poorly differentiated areas. Am J Surg Pathol. 1999;23:268-75.

Varela-Duran J, Enzinger FM. Calcifying synovial sarcoma. A clinicopathologic study of 32 cases. Cancer. 1982;50:345-52.

Mackenzie DH. Monophasic synovial sarcoma - a histological entity? Histopathology. 1977;1:151-7.

Miettinen M Lehto VP, Virtanen I. Monophasic synovial sarcoma of spindle cell type. Virchow arch. 1983,44:187-99.

John S, Brooks J. Disorders of soft tissue. In: Sternberg SS, Antonioli DA, Carter D, Eggleston JC. Sternberg’s Diagnostic Surgical Pathology.5th ed. Mills, Stacey E. 2010:173-174.

Miser JS, Triche TJ, Kinsella TJ, Pritchard DJ. Other soft tissue sarcomas of childhood. In: Pizzo PA, Poplack DG, eds. Principles and practice ofpediatric oncology, 3rd ed. Philadelphia: Lippincott- Raven. 1997:865-888.

Brennan MF, Alektiar KM, Maki RG. Sarcomas of the soft tissues and bones. In: DeVita VT Jr, Hellman S, Rosenberg SA, eds. Cancer: principles and practice of oncology, 6th ed. Philadelphia: Lippincott Williams and Wilkins. 2001:1841-1891.

Cadman NL, Soule EH, Kelly PJ. Synovial sarcoma: an analysis of 134 tumors. Cancer. 1965;18:613-27.

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Published

2016-12-21

Issue

Vol. 3 No. 3 (2016): July-September 2016

Section

Case Reports