DOI: http://dx.doi.org/10.18203/2349-3291.ijcp20162397

Monophasic synovial sarcoma: a case report and literature review

Ahana Gupta, Monika Choudhary, Neelu Gupta, Sunita Kulhari, Sandeep Pachar

Abstract


Synovial sarcoma is an aggressive soft tissue tumor which accounts for 7% - 8% of all human malignant sarcomas. Although this tumor generally affects adults, about 30% of reported cases occur in children and adolescents. Synovial sarcoma is the most common malignant non-rhabdomyosarcomatous soft tissue sarcoma in children and adolescents. We report a case of synovial sarcoma presented with pain and swelling in the left knee. MRI of left knee shows 25×54×56 mm soft tissue lesion in infrapatellar bursa. FNAC left knee swelling reported malignant spindle cell tumor. The mass was completely resected in a surgical procedure. In pathological examination of the mass, monomorphic fibroblastic synovial sarcoma was reported. Patient was treated with Ifosfamide and Adriamycin.


Keywords


Monophasic, Synovial sarcoma, Paediatric tumor

Full Text:

PDF

References


Enzinger FM, Weiss SW. Soft tissue tumors. 2nd ed. St. Louis: Mosby Company, 1988.

Baptista AM, Camarago OP, Croci AT, Oliveira CR. Synovial sarcoma of the extremities: prognostic factors for 20 nonmetastatic cases and a new histologic grading system with prognostic significance. Clinics, Sao Paulo. 2006;61(5):381-6.

Perez CA. Unusual nonepithelial tumors of head and neck. Principles and practice of radiation oncology. 1998;43:1125-34.

Weiss SW, Goldblum JR. Malignant Soft Tissue Tumors of Uncertain Type. In Weiss SW, Goldblum JR: Soft Tissue Tumors, 4th ed., St. Louis, Mosby, 2001.

Miettinen M, Virtanen I. Synovial sarcoma - a misnomer. Am J Pathol. 1984;117:18-25.

Bos GD, Esther RJ. Foot tumors: diagnosis and treatment. J Amer Acad Orthop Surg. 2002;10:259-70.

Machen SK, Easley KA, Goldblum JR. Synovial sarcoma of the extremities: a clinicopathologic study of 34 cases, including semi-quantitative analysis of spindled, epithelial, and poorly differentiated areas. Am J Surg Pathol. 1999;23:268-75.

Varela-Duran J, Enzinger FM. Calcifying synovial sarcoma. A clinicopathologic study of 32 cases. Cancer. 1982;50:345-52.

Mackenzie DH. Monophasic synovial sarcoma - a histological entity? Histopathology. 1977;1:151-7.

Miettinen M Lehto VP, Virtanen I. Monophasic synovial sarcoma of spindle cell type. Virchow arch. 1983,44:187-99.

John S, Brooks J. Disorders of soft tissue. In: Sternberg SS, Antonioli DA, Carter D, Eggleston JC. Sternberg’s Diagnostic Surgical Pathology.5th ed. Mills, Stacey E. 2010:173-174.

Miser JS, Triche TJ, Kinsella TJ, Pritchard DJ. Other soft tissue sarcomas of childhood. In: Pizzo PA, Poplack DG, eds. Principles and practice ofpediatric oncology, 3rd ed. Philadelphia: Lippincott- Raven. 1997:865-888.

Brennan MF, Alektiar KM, Maki RG. Sarcomas of the soft tissues and bones. In: DeVita VT Jr, Hellman S, Rosenberg SA, eds. Cancer: principles and practice of oncology, 6th ed. Philadelphia: Lippincott Williams and Wilkins. 2001:1841-1891.

Cadman NL, Soule EH, Kelly PJ. Synovial sarcoma: an analysis of 134 tumors. Cancer. 1965;18:613-27.