A rare case of 2, 4-Dichlorphenoxyacetic acid (2, 4-D) poisoning

Sanjay Singla, Sunny Malvia, Ram Prakash Bairwa, Mohammad Asif, Suresh Goyal


2,4-D (2,4-dichlorphenoxyacetic acid) is a selective herbicide which kills broad leaved plants but not grasses. It is not toxic to beneficial insects and has moderate mammalian toxicity. It is used widely in agriculture and forestry as an herbicide in either ester or salt formulation. Human poisoning with 2,4- D is rare and is generally following suicidal ingestion. Here we report a case of 2,4- D poisoning.


Alkaline diuresis, Dichlorphenoxyacetic acid, Poisoning

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Environmental health criteria. 2,4-dichlorphenoxyacetic acid (2,4-D) 29. Geneva: WHO; 1984.

Beasley VR, Arnold EK, Lovell RA, Parker AJ. 2, 4-D toxicosis. I: A pilot study of 2, 4-dichlorophenoxyacetic acid- and dicamba-induced myotonia in experimental dogs, Vet Hum Toxicol. 1991;33(5):435-40.

Garabrant DH, Philbert MA. Review of 2,4-dichlorphenoxyacetic acid (2,4-D) epidemiology and toxicity. Crit Rev Toxicol. 2002;32:233-57.

Bradberry SM, Proudfoot AT, Vale JA. Poisoning due to chlorphenoxy herbicides. Toxicol Rev. 2004; 23:65-73.

Flanagan RJ, Meredith TJ, Ruprah M, Onyon LJ, Liddle A. Alkaline diuresis for acute poisoning with chlorphenoxy herbicides and ioxynil. Lancet. 335;454-8.

Durakovic Z, Durakovic A, Durakovic S, Ivanovic D.Poisoning with 2,4-dichlorphenoxyacetic acid treated with haemodialysis. Arch Toxicol. 1992;66:518-21.