Renal involvement and outcome in children with COVID-19 infection
DOI:
https://doi.org/10.18203/2349-3291.ijcp20230721Keywords:
COVID-19, Pediatric, Renal involvement, Acute kidney injuryAbstract
Background: COVID-19 infection is known for multi-organ involvement of which Kidney injury predominates. AKI is associated with raised mortality in intensive care setting worldwide. Due to scarcity of data of renal involvement in pediatric COVID-19 population, we aimed to study its incidence in pediatric population requiring admission for COVID 19.
Methods: This was a single centred observational study where all the indoored COVID-19 infected children were looked for any form of renal involvement. We divided the study population into subgroups of those having any underlying renal ailment and the other without any underlying illness.
Results: 342 patients with COVID-19 infection were enrolled. Renal involvement was seen in 38 (11%) subjects. Of them 31 subjects developed AKI. Maximum number of population had severe/ stage III AKI (as per KDIGO criteria). Among the AKI subgroup (N=31), 41.9% (n= 13) required acute RRT of which 6 subjects were successfully discharged. 20/31 (64.5%) subjects of AKI subgroup were discharged with complete renal recovery and 11/31 (35.4%) had expired. Among the 7 subjects who did not develop AKI, all were discharged successfully.
Conclusions: AKI occurred in significant proportion of study population with SARS-Co-V2 infection. AKI subgroup reports higher mortality rate which is proportional to the stage of AKI.
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