Medical treatment of infected, ulcerative infantile hemangioma covered with pseudomembrane

Authors

  • Shadi A. Alsmadi Division of Neonatology, John H. Stroger, Jr. Hospital of Cook County, Chicago
  • Rebecca A. Megchelsen Division of Neonatology, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA
  • Similolu M. Akintorin Keck School of Medicine of USC, Los Angeles, USA
  • Allison L. Byrd Department of Pediatrics, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA
  • Manhal H. Khilfeh Division of Neonatology, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA

DOI:

https://doi.org/10.18203/2349-3291.ijcp20205101

Keywords:

Infantile hemangiomas, Pseudomembrane, Pseudomonas aeruginosa

Abstract

Infantile hemangiomas (IH) are benign vascular tumors in children which usually spontaneously resolve. Although these tumors are common, very few require treatment. If treatment is required, the hemangioma can be treated medically or surgically. The case described in this article is unique as it depicts a neonate with a large ulcerative IH which presented with a pseudomembrane covering the entire surface of the lesion and was subsequently found to be infected with Pseudomonas aeruginosa. The hemangioma was treated medically rather than surgically, and the medical management of this tumor resulted in the involution of the lesion and the healing of the ulcer.

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References

Léauté-Labrèze C, Harper JI, Hoeger PH. Infantile haemangioma. Lancet. 2017;390(10089):85-94.

Munden A, Butschek R, Tom W, Marshall JS, Poeltler DM, Krohne S, et al. Prospective study of infantile haemangiomas: incidence, clinical characteristics and association with placental anomalies. Br J Dermatol. 2014;170(4):907-13.

Cohen B, Puttgen A. Neonatal Dermatology. Pediatric Dermatology, Fourth Edition. Baltimore, Maryland: Elesvier. 2013:14-67.

Krowchuk DP, Frieden IJ, Mancini AJ, Darrow DH, Blei F, Greene AK, et al. Clinical Practice Guideline for the Management of Infantile Hemangiomas. Pediatrics. 2019;143(1).

Chang LC, Haggstrom AN, Drolet BA, Baselga E, Chamlin SL, Garzon MC, et al. Growth characteristics of infantile hemangiomas: implications for management. Pediatrics. 2008;122(2):360‐7.

Garzon MC, Epstein LG, Heyer GL, Frommelt PC, Orbach DB, Baylis AL, et al. PHACE syndrome: consensus-derived diagnosis and care recommendations. J Pediatr. 2016;178:24-33.

Iacobas I, Burrows PE, Frieden IJ, Liang MG, Mulliken JB, Mancini AJ, et al. LUMBAR: association between cutaneous infantile hemangiomas of the lower body and regional congenital anomalies. J Pediatr. 2010;157(5):795-801.

Rodriguez V, Lee A, Witman PM, Anderson PA. Kasabach-Merritt phenomenon: case series and retrospective review of the mayo clinic experience. J Pediatr Hematol Oncol. 2009;31:522-6.

Chamlin SL, Haggstrom AN, Drolet BA, Baselga E, Frieden IJ, Garzon MC, et al. Multicenter prospective study of ulcerated hemangiomas. J Pediatr. 2008;152(4):597.

Ricketts RR, Hatley RM, Corden BJ, Sabio H, Howell CG. Interferon-alpha-2a for the treatment of complex hemangiomas in infancy and childhood. Ann Surg. 1994;219(6):605-12.

Chang CS, Kang GC. Efficacious Healing of Ulcerated Infantile Hemangiomas Using Topical Timolol. Plast Reconstr Surg Glob Open. 2016;4(2).

Almebayadh M. Successful treatment of ulcerated infantile hemangioma with brimonidine-timolol cream: 2 cases report and review of the literature. J Dermatologic Treatment. 2019;31(4):433-4.

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Published

2020-11-24

How to Cite

Alsmadi, S. A., Megchelsen, R. A., Akintorin, S. M., Byrd, A. L., & Khilfeh, M. H. (2020). Medical treatment of infected, ulcerative infantile hemangioma covered with pseudomembrane. International Journal of Contemporary Pediatrics, 7(12), 2382–2386. https://doi.org/10.18203/2349-3291.ijcp20205101

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Section

Case Reports