Electrolyte disturbance in rotaviral diarrhea and other acute diarrheal diseases in children under 5 years

Authors

  • Keerthana T. N. Gubbari Department of Pediatrics, Sapthagiri Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20193728

Keywords:

Acute diarrheal disease, Electrolytes, Hypernatremia, Hyponatremia, Hyperkalemia, Hypokalemia, Rotavirus

Abstract

Background: Acute diarrheal disease is one of the most common cause of mortality and morbidity in under 5 children. Rotavirus is one of the important cause of diarrhea in under 5. This study was done to know the electrolyte disturbance in under 5 children with diarrhea.

Methods: A prospective observational study was conducted in Masonic Medical Centre for Children, Coimbatore on children aged less than 5 years with acute diarrhea with moderate and severe dehydration.

Results: Total 220 children are included in study, among them 66(58.9%) had rotavirus infection. Among 220 cases of diarrhea 14.09% (31/220) had hypernatremia, 2.72% (6/220) had hyponatremia, 4.54% (10/220) had hyperkalemia and 9.09% (20/220) had hypokalemia. Among 66 cases of rotavirus diarrhea, 27.27% (18/66) had hypernatremia, 4.5% (3/66) had hyponatremia and 25.75% (17/66) had hypokalemia.

Conclusions: Hypernatremia is the most common electrolyte disturbance in acute diarrheal diseases and most frequently seen in rotavirus diarrhea. In most of the situation, there is unavailability of laboratory or time lag in obtaining reports. Hence prediction of electrolyte disturbance and management is more important in diarrheal disease.

References

Zulfiqar AB. Acute Gastroenteritis in Children. RM Kliegman, BF Stanton, JWS Geme III, NF Schor, editor. Nelson textbook of pediatrics, 19th ed. Elsevier publishers; 2012: 1323-1339.

Morris SK, Awasthi S, Khera A, Bassani DG, Kang G, Parashar UD, et al. Rotavirus mortality in India: estimates based on a nationally representative survey of diarrhoeal deaths. Bulletin of the World Health Organization. 2012;90:720-7.

Ending preventable child deaths from pneumonia and diarrhea by 2025, the integrated global action plan for Pneumonia and Diarrhea (GAPPD) [internet]. Geneva. World Health Organization /UNICEF 2013. Available at: http://www.who.int/maternal_child_adolescent/documents/global_action_plan_pneumonia_diarrhea/en/.

Thomas GC, LK Pickering. Acute gastroenteritis. S Krugman, SL Katz, AA Gershon, CM Wilfert, editors. Infectious diseases of children, 111th Ed, USA: Mosby-Year Book, Inc.; 1992:105-126.

LK Pickering, CJ Baker, SS long, JA McMillan. Rotavirus infections, Red book 2006 Reports of the committee on infectious diseases. 27th ed. New York, American Academy of Pediatrics; 2006:572-575.

Shah GS, Das BK, Kumar S, Singh MK, Bhandari GP. Acid base and electrolyte disturbance in diarrhoea. Kathmandu Univ Med J (KUMJ). 2007;5(1):60-2.

JA Begam, MM Hoque, M Hussain, MNA Hasan, MH Molla, Impact of electrolyte disturbance in outcome of acute diarrhea in children, DS(child) H J. 2010;26(1):36-40.

Vishnu Murthy GS, Hospital Based Clinical Study of Hyponatremic dehydration and serum electrolyte profile in acute gastroenteritis, AIMS, Bellur, Karnataka, 2006. Available from: http://drvishnumurthy.blogspot.com. Accessed on 13 May 2010.

Shinjini B, Mona KC, Meherban Singh. Acute Gastroenteritis, Emergencies in pediatrics. 5th ed. New Delhi, Sagar publications; 2012: 385-405.

World Health Organization; Centre for Disease Control and Prevention: Diagnosis and management of foodborne illness [internet]. Chicago: Centre for Disease control and prevention; 2004. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5304al.htm. Accessed on 16 April 2004.

Mathew MA, Paulose A, Chitralekha S, Nair MK, Kang G, Kilgore P. Prevalence of rotavirus diarrhea among hospitalized under-five children. Ind Pediatr. 2014 Jan 1;51(1):27-31.

NS Chavan, Nilima T. Detection of human rotavirus and bacterial enteropathogen in acute gastroenteritis in children below 5 years of age in Wardha. Int J Curr Microbiol App Sci. 2014;3(6):288-91.

Nigel A. Cunliffe, J. Angela Booth, Claire Elliot, Sharon J. Lowe, Will Sopwith, Nick Kitchinand et al. Healthcare associated viral gastroenteritis among children in a large pediatric hospital, United Kingdom. Emerg Infect Dis. 2010 Jan;16(1):55-62.

Onyiriuka AN, Iheagwara EC. Serum electrolyte profiles of under-five Nigerian children admitted for severe dehydration due to acute diarrhea. Niger J Health Sci. 2015 Jan 1;15(1):14.

Mathew A, Rao PS, Sowmyanarayanan TV, Kang G. Severity of rotavirus gastroenteritis in an Indian population: report from a 3 year surveillance study. Vaccine. 2014 Aug 11;32:A45-8.

Zisu M, Camelia B, Carmen T, Maria SC, Roxana C, Laura FR, et al. Prevalence of Rotavirus infection among children in Galati, Romania. Analele Universitatii “Durarea de Jos” Din Galati. 2014;17(2):71-5.

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Published

2019-08-23

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Original Research Articles