Mortality and morbidity of very low birth weight and extremely low birth weight babies in neonatal period

Authors

  • Saroj Kumar Tripathy Department of Pediatrics, Gouri Devi Institute of Medical Sciences and Hospital, Rajbandh, Durgapur, West Bengal, India
  • Kripasindhu Chatterjee Department of Pediatrics, Gouri Devi Institute of Medical Sciences and Hospital, Rajbandh, Durgapur, West Bengal, India
  • Narendra Behera Department of Pediatrics, MKCG Medical College Hospital, Berhampur, Odisha, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20190704

Keywords:

Extremely low birth weight, Morbidity, Mortality, Preterm babies, Very low birth weight

Abstract

Background: Preterm birth is one of the major clinical problems in neonatology as it is commonly associated with perinatal mortality, serious neonatal morbidity and in some cases, it leads to childhood disability. The objective of this study was to find out the outcomes of VLBW and ELBW babies in the form of mortality and morbidity in neonatal period.

Methods: A cross sectional study was conducted in SNCU, MKCG Medical College, Berhampur, Odisha between 2011 to 2013. All babies with birth weight less than 1500gm, admitted between days 1 to day 7 of life were enrolled in the study. Babies were broadly divided in to two groups i.e.VLBW group (weight 1000-1499gm) and ELBW group (weight<1000gm). Details of antenatal history, sociodemographic profile and birth history including significant events were noted. Outcome measures included were death, cured and with sequelae.

Results: Total number of babies enrolled in this study were two hundred twelve (n=212) and following observations were made. Mortality of ELBW babies was 61.11% and that of VLBW babies was 26.41%. Death rate in babies with weight range 500-749gm, 750-999gm, 1000-1249gm and 125-1499gm was 87.50%, 53.57%, 30.76% and 20.97% respectively. It was found that morbidities such as RDS, HIE, shock and hypoglycemia are significantly higher in ELBW babies as compared to VLBW babies.

Conclusions: Extremely low birth weight babies have shown high mortality and morbidity compared to very low birth weight babies and its related death multiply when associated with complications like hyaline membrane disease, hypoxic ischemic encephalopathy, and sepsis.

Author Biography

Kripasindhu Chatterjee, Department of Pediatrics, Gouri Devi Institute of Medical Sciences and Hospital, Rajbandh, Durgapur, West Bengal, India

Pediatrician and Medical Faculty

References

Fanaroff AA, Stoll BJ, Wright LL, Carlo WA, Ehrenkranz RA, Stark AR, et al. Trends in neonatal morbidity and mortality for very low birthweight infants. Am J Obstetr Gynecol. 2007;196(2):147-e1.

Hakansson S, Farooqui A, Homgren PA, Serenius F, Hogberg U. Proactive management promotes outcome in extremely preterm infants:A population-based comparison of two perinatal management strategies. Pediatr. 2004;114: 58-64.

Itabashi K, Horiuchi T, Kusuda S, Kabe K, Itani Y, Nakamura T, et al. Mortality rates for extremely low birth weight infants born in Japan in 2005. Pediatr. 2009;123(2):445-50.

New Delhi: NIMS (ICMR) and UNICEF India Country Office. National Institute of Medical Statistics (NIMS), Indian Council of Medical Research (ICMR) and United Nations Children's Fund (UNICEF). Infant and child mortality in India: levels, trends and determinants 2012:40-50.

Intensive care nursery house staff manual, UCSF Children’s Hospital. Very low and extremely low birth weight infants, 2004: 65-68.

Sehgal A, Telang S, Passah SM, Jyothi MC. Maternal and neonatal profile and immediate outcome in ELBW babies. Indian pediatr. 2003 ;40(10):991-5.

Das C, Das CS. Morbidity and mortality pattern in level II neonatal care unit In Silchar (Abstract) Annual conference of National Neonatology Forum Guwahati, NNF 2001:72.

Shankaran S, Fanaroff AA, Wright LL, Stevenson DK, Donovan EF, Ehrenkranz RA, et al. Risk factors for early death among extremely low-birth-weight infants. Am J Obstetr Gynecol. 2002;186(4):796-802.

Roy KK, Baruah J, Kumar S, Malhotra N, Deorari AK, Sharma JB. Maternal antenatal profile and immediate neonatal outcome in VLBW and ELBW babies. Indian J Pediatr. 2006;73(8):669.

Mukhopadhyay K, Louis D, Mahajan R, Kumar P. Predictors of mortality and major morbidity in ELBW neonates. Indian Pediatr. 2013; 50(12):1119-23.

Barbara JS, Nellie IH, Rosemary DH. Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network. Pediatr, 2010; 126:443-56.

Larroque B, Ancel PY, Marret S, Marchand L, André M, Arnaud C, et al. Neurodevelopmental disabilities and special care of 5-year-old children born before 33 weeks of gestation (the EPIPAGE study): a longitudinal cohort study. Lancet. 2008;371(9615):813-20.

Basu S, Rathore P, Bhatia BD. Predictors of Mortality in Very low Birth weight neonates in India. Singapore Med J. 2008; 49(7):556-60.

Chien LY, Whyte R, Aziz K, Thiessen P, Matthew D, Lee SK. Improved outcome of preterm infants when delivered in tertiary care centers. Obstet. Gynecol. 2001;98:247-52.

Bang AT, Bang RA, Baitule SB, Reddy MH, Deshmukh MD. Effect of home-based neonatal care and management of sepsis on neonatal mortality: field trial in rural India. lancet. 1999;354(9194):1955-61.

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Published

2019-02-23

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Original Research Articles