Clear cell sarcoma of kidney: an uncommon paediatric neoplasm-two case reports and review of literature

Authors

  • Veeraraghavan Gurusamy Department of Pathology, Institute of Child Health, Madras Medical College, Chennai, India
  • Indumathi Karnan Department of Pathology, Institute of Child Health, Madras Medical College, Chennai, India
  • Pappathi Sadagopan Department of Pathology, Institute of Child Health, Madras Medical College, Chennai, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20164615

Keywords:

Bone metastases, Clear cell sarcoma, Late relapse, Wilms tumor

Abstract

Clear cell sarcoma of kidney is an uncommon neoplasm accounting for approximately 5% of all pediatric renal neoplasms, with a peak incidence between 1-3 years of age. Males are most commonly affected (M:F ratio – 2:1). It is a highly malignant neoplasm with a high propensity than other renal neoplasms to metastasize to bones, hence originally called as bone-metastasizing renal tumour of childhood by Marsden and Lawler. We describe here 2 case reports of clear cell sarcoma of kidney.  

References

Bone-metastasizing renal tumour of childhood. Marsden HB, Lawler W. British J Can. 1978;38(3):437-41.

Argani P, Perlman EJ, Breslow NE, Browning NG, Green DM, D'Angio GJ, et al. Clear cell sarcoma of the kidney: a review of 351 cases from the National Wilms Tumor Study Group Pathology Center. Am J Surg Pathol. 2000;24(1):4-18.

Gooskens SL, Furtwängler R, Vujanic GM, Dome JS, Graf N, van den Heuvel-Eibrink MM. Clear cell sarcoma of the kidney: a review. Eur J Cancer. 2012;48(14):2219-26.

Glass RB, Davidson AJ, Fernbach SK. Clear cell sarcoma of the kidney: CT, sonographic, and pathologic correlation. Radiology. 1991;180(3):715-7.

Watts KE, Hansel DE, MacLennan GT. Clear cell sarcoma of the kidney. J Urol. 2011;185(1):279-80.

Haas JE, Bonadio JF, Beckwith JB. Clear cell sarcoma of the kidney with emphasis on ultrastructural studies. Cancer. 1984;54(12):2978-87.

O'Meara E, Stack D, Lee CH, Garvin AJ, Morris T, Argani P, et al. Characterization of the chromosomal translocation t (10;17)(q22;p13) in clear cell sarcoma of kidney. J Pathol. 2012;227(1):72-80.

Zhuge Y, Cheung MC, Yang R, Perez EA, Koniaris LG, Sola JE. Pediatric Non-Wilms renal tumors: subtypes, survival, and prognostic indicators. J Surg Res. 2010;156(2):257-63.

Downloads

Published

2016-12-21